Renal Injury Associated With Human Immunodeficiency Virus Infection and Therapy Arthur H. Cohen Cynthia C. Nast It was within 3 years of the initial description of the acquired immunodeficiency syndrome…
C3 Glomerulopathies, Including Dense Deposit Disease H. Terence Cook Matthew C. Pickering C3 glomerulopathy is a recently introduced term (1) that encompasses glomerular disease characterized by the accumulation in the…
Focal Segmental Glomerulosclerosis Vivette D. D’Agati M. Barry Stokes Focal segmental glomerulosclerosis (FSGS) refers to a pattern of glomerular scarring that affects a subset of glomeruli (i.e., focal) and involves…
Membranoproliferative Glomerulonephritis Xin J. (Joseph) Zhou Fred G. Silva Membranoproliferative glomerulonephritis (MPGN) refers to a morphologic pattern that includes many etiologically distinct forms of glomerulonephritis in which, as the name…
Membranous Glomerulonephritis Glen S. Markowitz Vivette D. D’Agati BACKGROUND Definition Membranous glomerulonephritis (MGN) is a pathologic diagnosis defined by the presence of subepithelial immune deposits that induce a spectrum of…
Cystic Diseases and Developmental Kidney Defects Helen Liapis Paul J.D. Winyard CYSTIC KIDNEY DISEASES Cystic kidney diseases are heterogeneous in origin, distribution, and pathogenesis. Cysts usually originate in the tubules…
The Nephrotic Syndrome and Minimal Change Disease Jean L. Olson The kidney is an efficient ultrafilter, and urinary protein loss is only 80 to 150 mg per day in the…
Renal Anatomy and Histology Stephen M. Bonsib The focus of this chapter is the gross anatomy, histology, and ultrastructure of the kidney, a remarkably complex organ that fosters exploration into…
Primer on the Pathologic Classification and Diagnosis of Kidney Disease J. Charles Jennette Fred G. Silva Jean L. Olson Vivette D. D’Agati This chapter begins with a very brief history…
Development of the Kidney Adrian S. Woolf Dagan Jenkins Developmental kidney disorders account for a wide spectrum of disease in fetuses, children, and adults (1,2,3,4,5,6). As assessed by registries from…
