NEPHROLOGY

Catalytic (Labile) Iron in Kidney Disease

Jun 6, 2019 by in NEPHROLOGY Comments Off on Catalytic (Labile) Iron in Kidney Disease

Introduction Despite advances in understanding the pathophysiology of acute kidney injury (AKI) and chronic kidney disease, treatment for kidney disease remains unsatisfactory. In this chapter, we briefly recount the importance…

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Renal Physiology and Disease in Pregnancy

Jun 6, 2019 by in NEPHROLOGY Comments Off on Renal Physiology and Disease in Pregnancy

The urinary system, volume homeostasis, osmoregulation, and composition of body fluids are all altered in normal pregnancy. There are also hemodynamic changes involving cardiac output and blood pressure. Knowledge of…

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Pathogenesis and Treatment of Nephrolithiasis

Jun 6, 2019 by in NEPHROLOGY Comments Off on Pathogenesis and Treatment of Nephrolithiasis

Kidney Stones A majority of patients form stones containing calcium oxalate (CaOx) and calcium phosphate (CaP). Of these most form predominantly CaOx stones in the absence of systemic disease, so…

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Cellular Mechanisms of Drug Nephrotoxicity

Jun 6, 2019 by in NEPHROLOGY Comments Off on Cellular Mechanisms of Drug Nephrotoxicity

This review will trace the general mechanisms of renal cell injury before focusing on selected specific nephrotoxins that demonstrate the key principles of injury. Potentially, all of the cellular events…

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Immunologic Mechanisms of Vasculitis

Jun 6, 2019 by in NEPHROLOGY Comments Off on Immunologic Mechanisms of Vasculitis

The kidneys are among the organs most commonly affected by systemic vasculitis. This chapter reviews the etiology and pathogenesis of forms of vasculitis that most often affect the kidneys. The…

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