Pharmacologic Therapies for Obesity
This article examines the transitions in pharmacological therapy for obesity. It reviews the current options approved by the Food and Drug Administration and several drugs approved for other indications that…
GASTROENTEROLOGY
Hepatic Complications of Obesity
Obesity is associated with a spectrum of chronic liver disease. Because obesity increases the risk for advanced forms of liver disease (ie, cirrhosis and liver cancer), the obesity epidemic is…
Colonic Complications of Obesity
Obesity is a risk factor for colorectal cancer and adenomatous polyps. The increased prevalence of neoplasia coupled with the observation that obesity may be associated with a suboptimal bowel preparation…
Gastrointestinal Symptoms and Diseases Related to Obesity: An Overview
Obesity is a leading cause of illness and death worldwide. It is a risk factor for many common gastrointestinal symptoms and digestive disorders, including many cancers. Disruption of mechanisms that…
Gastroesophageal Reflux Disease and Obesity
Gastroesophageal reflux disease (GERD) is a common condition, with multifactorial pathogenesis, affecting up to 40% of the population. Obesity is also common. Obesity and GERD are clearly related, both from…
Prevalence and Epidemiology of Gastrointestinal Symptoms Among Normal Weight, Overweight, Obese and Extremely Obese Individuals
Until recently, the epidemiology of gastrointestinal (GI) symptoms had not been adequately studied in relation to increasing body mass index. To date there are only a few studies in the…
The Epidemiology of Obesity
Obesity has received considerable attention as a major health hazard because of the increase in the prevalence of obesity not only in the United States but also in several other…
Acute Acalculous Cholecystitis
Acute acalculous cholecystitis (ACC) can develop with or without gallstones after surgery and in critically ill or injured patients. Diabetes mellitus, malignant disease, abdominal vasculitis, congestive heart failure, cholesterol embolization,…
Functional Gallbladder Disorder: Gallbladder Dyskinesia
Functional gallbladder disorder, commonly referred to as gallbladder dyskinesia, is characterized by the occurrence of abdominal pain resembling gallbladder pain but in the absence of gallstones. The diagnosis and management…
Diagnosis and Management of Gallbladder Polyps
Gallbladder polyps are frequently encountered on cross-sectional imaging, often in asymptomatic patients. Most are benign and of little clinical importance. However, some polyps do have a malignant potential. This article…