Management of Sickle Cell Anemia

Apr 8, 2018 by in NEPHROLOGY Comments Off on Management of Sickle Cell Anemia

Fig. 13.1 Red blood cells of a patient with sickle-cell disease. Left: Oxygenated. Right: Deoxygenated. The shape of the cells when deoxygenated causes them to break easily. [Courtesy of Dr….

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Post-Transplant Anemia

Apr 8, 2018 by in NEPHROLOGY Comments Off on Post-Transplant Anemia

(a) Blood loss anemia   Intraoperative blood loss   Repeated blood draws—phlebotomy   Gastrointestinal   Menstrual blood losses (b) Decreased RBC production  Decreased effective production   Iron deficiency—absolute or functional   Folate deficiency—medications   Pure red cell…

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Anemia in Malignancy

Apr 8, 2018 by in NEPHROLOGY Comments Off on Anemia in Malignancy

Grade Symptom severity Hemoglobin values 0 Within normal limits 12.0–16.0 g/dL for women and 14.0–18.0 g/dL for men 1 Mild 10 g/dL to levels within normal limits 2 Moderate 8.0–10.0 g/dL 3 Serious/severe 6.5–7.9 g/dL…

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Current and Novel Drugs for Management of Anemia

Apr 8, 2018 by in NEPHROLOGY Comments Off on Current and Novel Drugs for Management of Anemia

Fig. 5.1 Normal erythropoiesis. The hematopoietic stem cell (HSC), once committed, differentiates into the blast-forming units—erythroid (BFU-E) that in turn differentiates into the colony-forming unit—erythroid (CFU-E). The proerythroblast (Pro-EB), the…

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Anemia in Liver Disease

Apr 8, 2018 by in NEPHROLOGY Comments Off on Anemia in Liver Disease

Acute blood loss anemia (portal hypertension-related)  Esophageal varices  Gastric varices  Rectal varices Chronic blood loss anemia  Portal hypertensive gastropathy  Portal hypertensive enteropathy  Portal hypertensive colopathy  Gastric-antral vascular ectasia Acute hemolytic…

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Disease State: Kidney Disease

Apr 8, 2018 by in NEPHROLOGY Comments Off on Disease State: Kidney Disease

Method Equation Cockcroft-Gault [(140—Age in years) × (Weight in kg) × (0.85 if female)]/(72 × Scr in mg/dL) MDRD 186 × (Scr)−1.154 × (Age)−0.203 × (0.742 if female) × (1.212 if African American) CKD-EPI A × (Scr/B)C × (0.993)Age A: African American female = 166; African American male = 163;…

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Anemia of Chronic Kidney Disease

Apr 8, 2018 by in NEPHROLOGY Comments Off on Anemia of Chronic Kidney Disease

  Oral agents Intravenous agents Most common agents Ferrous fumarate Ferric gluconate Ferrous gluconate Ferumoxytol Ferrous sulfate Iron sucrose Polysaccharide-iron complex  Side effects Gastrointestinal (metallic taste, flatulence, constipation, diarrhea, abdominal…

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Nutritional Anemia in Adults and in Elderly Patients

Apr 8, 2018 by in NEPHROLOGY Comments Off on Nutritional Anemia in Adults and in Elderly Patients

Etiology Prevalence (%) Chronic inflammation (chronic disease) 23.0 Iron deficiency 18 Renal failure 9 Liver disease and endocrine disease (chronic disease) 7 Posthemorrhagic 7 Folate deficiency 6 Myelodysplasia 5 Vitamin…

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The Complex Relationships Between Iron Regulation, Obesity, and Anemia

Apr 8, 2018 by in NEPHROLOGY Comments Off on The Complex Relationships Between Iron Regulation, Obesity, and Anemia

© Springer Science+Business Media LLC 2018Robert Provenzano, Edgar V. Lerma and Lynda Szczech (eds.)Management of Anemiadoi.org/10.1007/978-1-4939-7360-6_10 10. The Complex Relationships Between Iron Regulation, Obesity, and Anemia Stephen Z. Fadem1   (1) Department of Medicine, Baylor College of Medicine, 6624…

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