Transplantation Immunobiology

Feb 24, 2019 by in NEPHROLOGY Comments Off on Transplantation Immunobiology

Outline The Alloimmune Response, 555 A. Transplantation Antigens, 555 B. Cellular Events Leading to Allograft Rejection, 558 Tolerance, 567 Summary, 569 When an organ or tissue from one member of…

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Pediatric Renal Transplantation

Feb 24, 2019 by in NEPHROLOGY Comments Off on Pediatric Renal Transplantation

Abstract: Kidney transplantation in children involves many unique aspects. Surgical techniques are different in small children. Routine childhood immunizations may not be complete before transplantation. Growth is suboptimal in chronic…

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Diagnosis and Therapy of Graft Dysfunction

Feb 24, 2019 by in NEPHROLOGY Comments Off on Diagnosis and Therapy of Graft Dysfunction

Abstract Graft dysfunction is a problematic complication of kidney transplantation. The diagnosis and treatment varies by the time period after transplantation. This chapter reviews the major etiologies of graft dysfunction…

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Chronic Kidney Disease in the Kidney Transplant Recipient

Feb 24, 2019 by in NEPHROLOGY Comments Off on Chronic Kidney Disease in the Kidney Transplant Recipient

Abstract A significant proportion of prevalent kidney transplant recipients (KTRs) will have decreased kidney function and be at risk for chronic kidney disease (CKD)-related complications, including cardiovascular disease, mineral and…

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Acute Kidney Injury Diagnostics and Biomarkers

Feb 24, 2019 by in NEPHROLOGY Comments Off on Acute Kidney Injury Diagnostics and Biomarkers

Abstract The diagnosis of acute kidney injury (AKI) has relied on serum creatinine and urine output, two biomarkers that are insensitive and nonspecific, particularly early in the course of the…

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Peritoneal Dialysis Solutions, Prescription and Adequacy

Feb 24, 2019 by in NEPHROLOGY Comments Off on Peritoneal Dialysis Solutions, Prescription and Adequacy

Abstract: This chapter addresses peritoneal dialysis solutions, peritoneal dialysis adequacy, and prescriptions and residual kidney function. Keywords biocompatible, glucose degradation products, glucose polymer solutions, PD adequacy, PD solutions, peritoneal membrane…

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The Epidemiology of Acute Kidney Injury

Feb 24, 2019 by in NEPHROLOGY Comments Off on The Epidemiology of Acute Kidney Injury

Abstract Acute kidney injury (AKI) is characterized by sudden (i.e., hours to days) impairment of kidney function. AKI is an increasingly common complication in hospitalized individuals around the world and…

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