IgA Nephropathy and IgA Vasculitis (Henoch-Schönlein Purpura) Nephritis Mark Haas HISTORICAL BACKGROUND IgA nephropathy first became recognized as a distinct entity in 1968, when Berger and Hinglais (1) reported a…
Alport Syndrome, Familial Benign Hematuria, Nail-Patella Syndrome, Type III Collagen Glomerulopathy, and Pierson Syndrome Marie Claire Gubler Laurence Heidet Corinne Antignac ALPORT SYNDROME In 1927, Alport (1) reported the association…
Acute Postinfectious Glomerulonephritis and Glomerulonephritis Caused by Persistent Bacterial Infection Anjali A. Satoskar Tibor Nadasdy Fred G. Silva Bacterial infection outside the kidney can lead to glomerulonephritis either after the…
Renal Injury Associated With Human Immunodeficiency Virus Infection and Therapy Arthur H. Cohen Cynthia C. Nast It was within 3 years of the initial description of the acquired immunodeficiency syndrome…
C3 Glomerulopathies, Including Dense Deposit Disease H. Terence Cook Matthew C. Pickering C3 glomerulopathy is a recently introduced term (1) that encompasses glomerular disease characterized by the accumulation in the…
Focal Segmental Glomerulosclerosis Vivette D. D’Agati M. Barry Stokes Focal segmental glomerulosclerosis (FSGS) refers to a pattern of glomerular scarring that affects a subset of glomeruli (i.e., focal) and involves…
Membranoproliferative Glomerulonephritis Xin J. (Joseph) Zhou Fred G. Silva Membranoproliferative glomerulonephritis (MPGN) refers to a morphologic pattern that includes many etiologically distinct forms of glomerulonephritis in which, as the name…
Membranous Glomerulonephritis Glen S. Markowitz Vivette D. D’Agati BACKGROUND Definition Membranous glomerulonephritis (MGN) is a pathologic diagnosis defined by the presence of subepithelial immune deposits that induce a spectrum of…
Cystic Diseases and Developmental Kidney Defects Helen Liapis Paul J.D. Winyard CYSTIC KIDNEY DISEASES Cystic kidney diseases are heterogeneous in origin, distribution, and pathogenesis. Cysts usually originate in the tubules…
The Nephrotic Syndrome and Minimal Change Disease Jean L. Olson The kidney is an efficient ultrafilter, and urinary protein loss is only 80 to 150 mg per day in the…
