Thrombotic Microangiopathies Zoltan G. Laszik Neeraja Kambham Fred G. Silva Thrombotic microangiopathy (TMA) is the pathologic term for a condition characterized by microvascular changes including thrombosis in association with laboratory…
Renal Disease in Pregnancy Agnes B. Fogo EFFECTS OF NORMAL PREGNANCY ON THE KIDNEY Structural Changes in Pregnancy Pregnancy normally induces changes in kidney function. In some women, complications of…
Anti-Glomerular Basement Membrane Glomerulonephritis and Goodpasture Syndrome J. Charles Jennette Volker Nickeleit BACKGROUND INFORMATION Anti-GBM Disease In 1919, Ernest Goodpasture (1) reported an 18-year-old male patient who developed hemoptysis and…
Pauci-Immune and Antineutrophil Cytoplasmic Autoantibody-Mediated Crescentic Glomerulonephritis and Vasculitis J. Charles Jennette David B. Thomas A landmark publication in 1979 by Stilmant et al. (1) reported that many if not…
Renal Involvement in Polyarteritis Nodosa, Kawasaki Disease, Takayasu Arteritis, and Giant Cell Arteritis J. Charles Jennette Harsharan K. Singh BACKGROUND Nomenclature of Systemic Vasculitis Vasculitis is vessel wall inflammation. Perivascular…
IgA Nephropathy and IgA Vasculitis (Henoch-Schönlein Purpura) Nephritis Mark Haas HISTORICAL BACKGROUND IgA nephropathy first became recognized as a distinct entity in 1968, when Berger and Hinglais (1) reported a…
Alport Syndrome, Familial Benign Hematuria, Nail-Patella Syndrome, Type III Collagen Glomerulopathy, and Pierson Syndrome Marie Claire Gubler Laurence Heidet Corinne Antignac ALPORT SYNDROME In 1927, Alport (1) reported the association…
Acute Postinfectious Glomerulonephritis and Glomerulonephritis Caused by Persistent Bacterial Infection Anjali A. Satoskar Tibor Nadasdy Fred G. Silva Bacterial infection outside the kidney can lead to glomerulonephritis either after the…
Renal Injury Associated With Human Immunodeficiency Virus Infection and Therapy Arthur H. Cohen Cynthia C. Nast It was within 3 years of the initial description of the acquired immunodeficiency syndrome…
C3 Glomerulopathies, Including Dense Deposit Disease H. Terence Cook Matthew C. Pickering C3 glomerulopathy is a recently introduced term (1) that encompasses glomerular disease characterized by the accumulation in the…
