Systemic Therapy for Metastatic Renal Cell Carcinoma
Renal cell cancer (RCC) is the most common form of cancer of the kidney and accounts for approximately 44,000 cases per year in the United States. Historically, only immunotherapy showed…
Resection of Renal Tumors Invading the Vena Cava
Surgical resection of renal cell carcinoma remains the mainstay for the management of patients who suffer from this disease. Five percent to 10% of renal cell carcinomas develop a tumor…
Surgical Intervention in Patients with Metastatic Renal Cancer: Metastasectomy and Cytoreductive Nephrectomy
For patients with metastatic renal cancer, prognostic factors defined in systemic therapy clinical trials stratify patients into good, intermediate, and poor risk groups with median survival varying from 4 to…
Lymph Node Dissection in the Management of Renal Cell Carcinoma
Radical nephrectomy and regional lymphadenectomy have been the cornerstone of therapy for renal cell carcinoma for several decades; however, debate regarding the potential advantages of lymph node dissection for renal…
Choice of Operation for Clinically Localized Renal Tumor
The cornerstone of treatment for localized renal tumors is surgical excision, which until recently was accomplished primarily through radical nephrectomy. The last 2 decades have seen a rapid evolution in…
Renal Tumor Natural History: the Rationale and Role for Active Surveillance
Renal cell carcinoma (RCC) is the most common malignancy of the kidney. Despite widespread treatment at diagnosis, overall mortality rates associated with RCC have not decreased. Partly because of the…
The Medical and Oncological Rationale for Partial Nephrectomy for the Treatment of T1 Renal Cortical Tumors
This article presents the oncological and medical rationale for partial nephrectomy as the treatment of choice whenever possible for T1 renal tumors. The value of partial nephrectomy in the management…
Prognostic Models and Algorithms in Renal Cell Carcinoma
Although surgical treatment is curative for localized renal cell carcinoma (RCC), 25% of patients present with locally advanced or disseminated disease, and disease will recur systemically in another 20% to…
Contemporary Radiologic Imaging of Renal Cortical Tumors
Contemporary radiologic imaging has resulted in an increasing number of smaller renal cortical tumors being identified. The ability of imaging to classify these tumors is limited, although certain features may…
Molecular Imaging of Renal Cell Carcinoma
The recent identification of agents that have significantly influenced the therapy of clear cell renal carcinoma and the decreasing size of renal masses, usually detected serendipitously, have led to a…
