Fig. 18.1 Glomerular capillary wall showing thickening and widening (arrows) with basement membrane splitting and lamellations (basket-weave appearance). Note extensive foot process effacement. (x6000). Courtesy Dr. Sanjeev Sethi, Mayo Clinic…
1 Antiphospholipid syndrome 2 Systemic lupus erythematosus 3 Systemic scleroderma 4 Malignant hypertension 5 Pregnancy-HELLP syndrome 6 Drugs 7 Malignancy 8 Solid organ transplant 9 Allogeneic stem cell transplant—ionizing radiation…
Fig. 2.1 Electron microscopy of a glomerulus from a renal biopsy of a patient with minimal change disease, showing diffuse foot process effacement (white arrows) and microvillous degenerative changes (black…
Fig. 17.1 A biopsy of a mass lesion in a 62-year-old man shows an expansile “storiform” interstitial fibrosis with marked interstitial inflammation. A silver stain (upper left panel) highlights tubular…
93. Baudouin V, Alberti C, Lapeyraque AL, Bensman A, Andre JL, Broux F, et al. Mycophenolate mofetil for steroid-dependent nephrotic syndrome: a phase II Bayesian trial. Pediatr Nephrol. 2012;27(3):389–96.PubMed 94….
89. Jayne DR, Gaskin G, Rasmussen N, et al. Randomized trial of plasma exchange or high-dosage methylprednisolone as adjunctive therapy for severe renal vasculitis. J Am Soc Nephrol. 2007;18(7):2180–8.PubMedCrossRef 90….
Fig. 16.1 Inherited endocrine condition related to mineralocorticoid excess. The picture shows the molecular pathways involved in dysregulation of NaCl homeostasis located in the distalrenal tubules. AME apparent mineralocorticoid excess;…
(1) Department of Physiology and Biophysics, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA KeywordsPregnancyHypertensionAngiogenic factorsPlacentalKidneyVEGFImmune mechanismsNitric oxideEndothelin Introduction Preeclampsia (PE) is considered a pregnancy-specific…
Fig. 7.1 Practical recommendations for the use of renal denervation in clinical practice according to the European Society of Hypertension. (Reprinted from Schmieder et al. [23]. With permission from Wolters…
Fig. 12.1 Uric acid metabolism. Purines are degraded to hypoxanthine and xanthine. Xanthine oxidase converts hypoxanthine to xanthine and also xanthine to uric acid. Unlike most other animals, humans and…
