Fig. 16.1 Inherited endocrine condition related to mineralocorticoid excess. The picture shows the molecular pathways involved in dysregulation of NaCl homeostasis located in the distalrenal tubules. AME apparent mineralocorticoid excess;…
(1) Department of Physiology and Biophysics, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA KeywordsPregnancyHypertensionAngiogenic factorsPlacentalKidneyVEGFImmune mechanismsNitric oxideEndothelin Introduction Preeclampsia (PE) is considered a pregnancy-specific…
Fig. 12.1 Uric acid metabolism. Purines are degraded to hypoxanthine and xanthine. Xanthine oxidase converts hypoxanthine to xanthine and also xanthine to uric acid. Unlike most other animals, humans and…
Fig. 7.1 Practical recommendations for the use of renal denervation in clinical practice according to the European Society of Hypertension. (Reprinted from Schmieder et al. [23]. With permission from Wolters…
Traditional factors Family history (essential HTN) Obesity Tumor (e.g., pheochromocytoma, Wilms, neuroblastoma) Neurologic (e.g., dysautonomia) Cardiovascular (coarctation, renal artery stenosis, middle aortic syndrome) Chronic lung disease, obstructive sleep apnea Endocrine…
Fig. 14.1 Hypertension induces inflammatory processes. Hypertension can promote inflammatory events within the vascular wall and the kidney. Increased sympathetic nerve activity (SNA) can drive both hypertension and immune cells…
Fig. 1.1 JNC overview of systolic BP. To simplify the classification of hypertension, the seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood…
15. Snyder JJ, et al. Body size and outcomes on peritoneal dialysis in the United States. Kidney Int. 2003;64(5):1838–44.CrossRef 16. Johansen KL, et al. Association of body size with outcomes…
Fig. 15.1 Reference SNP associations for HTN, SBP, and DBP plotted by chromosomal location. SNP single-nucleotide polymorphism, HTN hypertension, SBP systolic blood pressure, DBP diastolic blood pressure Table 15.1 Overview…
Fig. 9.1 Structure of the CYT006-AngQb vaccine. The modified angiotensin II peptide is composed of the amino acid sequence of Ang Iotensin1–8 octapeptide (Angiotensin II) fused at its N-terminus to…
