Fig. 36.1 Pathophysiological mechanisms of congenital disorders of intestinal electrolytes transport. 1 Familial diarrhea syndrome is due to a mutation in intestinal guanylate cyclase receptor (GC-C) for the endogenous ligands…
Biliary excretion is the only mechanism for copper elimination under physiological conditions, and it increases with increasing size of the hepatic copper pool. Trafficking of copper in and through the…
Fig. 33.1 Early acute pancreatitis. Note edematous gland (black arrow) with a small amount of fluid (small arrow). No visible ducts or calcifications. (Images courtesy of Dr. David Gregg) Pathophysiology…
All anatomical areas Giardiasis Granulation tissue polyps Inflammatory bowel disease Lymphangiectasia Lymphoma Multiple adenomatous or hyperplastic polyps Metastatic tumours Familial and sporadic gastrointestinal polyposes Ganglioneuromatosis Neuroendocrine hyperplasia and neoplasia Stomach …
Fig. 10.1 Pathophysiologic mechanisms for GER. (Reproduced from Ref. [29], with permission from John Wiley and Sons) GER occurs during episodes of TLESR or inadequate adaptation of the sphincter tone…
(1) Department of Translational Medical Sciences, Section of Pediatrics, University of Naples “Federico II”, Via S. Pansini 5, 80131 Naples, Italy Massimo Martinelli Email: staiano@unina.it KeywordsHirschsprung’s diseaseIntestinal neuronal dysplasiaRectal suction…
Fig. 46.1 Possible routes for EN EN is used to preserve nutritional status, support normal growth, and treat malnutrition when oral feeding is inadequate or not possible. EN is more…
Chagas disease Tumors (e.g., leiomyoma, Hodgkin’s disease, gastric carcinoma; “pseudoachalasia”) Sarcoidosis Hereditary cerebellar ataxia Eosinophilic esophagitis Hirschsprung’s disease Chronic idiopathic intestinal pseudo-obstruction Multiple endocrine neoplasia type 2b Miscellaneous (e.g., juvenile…
Idiopathic Genetic • PRSS1 • CFTR • SPINK1 • CTRC • CPA1 • CEL Drugs (l-asparaginase, valproate, metronidazole, azathioprine, tetracycline, pentamidine, etc.) • Metabolic disease • Hyperlipidemia • Hypercalcemia •…
Fig. 59.1 a, b Xanthomas on the hands of a child with Alagille syndrome The natural history of the liver disease in ALGS has a unique course. For those children…
