Liver Disease in Renal Transplant Recipients

Mar 5, 2017 by in NEPHROLOGY Comments Off on Liver Disease in Renal Transplant Recipients

Type of liver insult Setting Characteristic findings Ischemic hepatic injury Hypotension during surgery but may also occur with severe volume depletion and hepatic hypoperfusion at any time posttransplant Marked but…

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Wait List Management

Mar 5, 2017 by in NEPHROLOGY Comments Off on Wait List Management

Fig. 4.1 United Network for Organ Sharing national kidney wait list additions and composition by active status Facts and Figures Since UNOS began keeping records in 1987, over 500,000 organ…

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The Prevention and Treatment of Coronary Artery Disease in Kidney Transplant Recipients

Mar 5, 2017 by in NEPHROLOGY Comments Off on The Prevention and Treatment of Coronary Artery Disease in Kidney Transplant Recipients

Dyslipidemia Goal Initiate Increase Alternative TG > 500 mg/dL with LDL < 100 mg/dL TG < 500 mg/dL TLC TLC + niacin Fibrate or statin LDL 100–129 mg/dL LDL < 100 mg/dL TLC TLC + low-dose statin Ezetimibe or niacin LDL > 100 mg/dL…

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Hematologic Complications of Transplantation

Mar 5, 2017 by in NEPHROLOGY Comments Off on Hematologic Complications of Transplantation

Medication Mechanism Incidence References mTOR inhibitors Myelosuppression 10–45 % [31] Antithymocyte globulins Myelosuppression, DITP 10–44 % [6, 19] Valproate DITP, myelosuppression 5–30 % [55] Azathioprine Myelosuppression 10–15 % [51] Ganciclovir/valganciclovir…

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Drug Interactions in Solid Organ Transplant Recipients

Mar 5, 2017 by in NEPHROLOGY Comments Off on Drug Interactions in Solid Organ Transplant Recipients

Immunosuppressive agent Interacting agent Effect of interacting agent Recommendations/monitoring Calcineurin inhibitors   Antifungals Anidulafungin No significant effect  Amphotericin B Increased risk of nephrotoxicity Appropriate hydration; monitor renal function closely Caspofungin…

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