Molecular Imaging of Renal Cell Carcinoma
The recent identification of agents that have significantly influenced the therapy of clear cell renal carcinoma and the decreasing size of renal masses, usually detected serendipitously, have led to a…
UROLOGY
Epidemiology, Clinical Staging, and Presentation of Renal Cell Carcinoma
The increasing incidence of renal cell carcinoma over the past 2 decades can be partly explained by the expanding use of abdominal imaging. As a result, the most incident renal…
Pathologic Features of Renal Cortical Tumors
Our better understanding of the morphologic spectrum of renal cortical tumors has resulted in a clinically more relevant classification of these tumor types. We now recognize that “granular cell” and…
Molecular Biology of Renal Cortical Tumors
The last 10 years have witnessed a dramatic evolution in our understanding of renal cell carcinoma (RCC) biology, which has led to the development of novel medical therapies and revolutionized…
Familial and Hereditary Renal Cancer Syndromes
Hereditary and familial forms of kidney cancer are encountered routinely in urologic practice. Discoveries in the genetic and molecular biology of these diseases have had a critical impact on the…
Surgical Management of Renal Tumors: A Historical Perspective
The modern era of renal surgery began on August 2, 1869 when the first planned nephrectomy on a living human being was performed. Eighteen years later in 1887, the first…
Medical Malpractice: The Good, the Bad, and the Ugly
The underpinning of medical practice has always been patient care and patient safety. The past several decades, however, have seen an erosion of the patient-doctor relationship. A number of factors…
The Evolution of Health Care in America
The evolution of health care in America had its beginnings even before the founding of the nation. This article divides the evolution of American health care into six historical periods:…
The Sad and Bleak Future for Urology Funding at the National Institutes of Health
The bulk of federal funding for medical research is delivered through the National Institutes of Health (NIH). Because federal funding is coordinated through the annual discretionary budget review process, the…
Supergroups and Economies of Scale
With the changing environment for medical practice, physician practice models will continue to evolve. These “supergoups” create economies of scale, but their advantage is not only in the traditional economic…
