Fig. 10.1 Spectrum of alcoholic liver disease and main modifying factors. The percentage represents the patients who progress from one stage to the next Alcohol-induced steatosis is characterized by the…
End points related to how a patient feels – Quality of life End points related to how a patient functions – Days from work lost – Ability to carry on…
Author, year [ref.] Country/setting/period Study design/cohort definition/control group Number of patients/follow-up HCC incidence in cohort vs. control group HCC mortality in cohort vs. control group Sorensen et al., 1998 [57]…
Author, year Country Population Sample size (n) Prevalence of NAFLD (%) Mode of diagnosis Ref. No. Price, 2014 USA HIV+ and HIV− men in the Multicenter AIDS Cohort Study. N = 719…
Model Description Advantages Limitations Methionine-choline-deficient diet (MCD) •High-sucrose (40 %) and high-fat (10–20 %) diet lacking methionine and choline •Impaired VLDL assembly and β-oxidation of fatty acids •Day 10: NASH…
Author Comparators N Population Findings ALT Larrieta-Carrasco et al. [58] ALT ≤ or >35 U/L 1037 Overweight Mexican children aged 6–12 PNPLA3 GG genotype had 3.7 times the odds for…
Fig. 29.1 An isolated apoptotic body in a crypt. Less than six apoptotic bodies per ten crypt cross sections are seen in cases graded as indeterminate for acute rejection (H&E…
Fig. 26.1 Patient candidate for abdominal wall transplantation. The wall is severely damaged from repeated laparotomies and enterocutaneous fistulae Fig. 26.2 At the end of bowel transplantation, the recipient abdominal…
