Benign Hepatocellular Tumors
Fig. 4.1 Focal nodular hyperplasia, gross. The lesion is lobulated and firm to rubbery. It is well-circumscribed but unencapsulated and often bulges from the liver on cut surface. The background…
Metastatic Tumors
Fig. 15.1 Cirrhotic liver with metastatic breast carcinoma. Tumor cells are seen within the fibrous septa and in the cirrhotic nodule Fig. 15.2 Cirrhotic liver with metastatic breast carcinoma. High-power…
Hepatocellular Carcinoma
Fig. 7.1 Aberrant arteriole in tumor. Aberrant small arteries in the lobules are useful features that support a diagnosis of neoplasm. However, this feature is not specific for tumors and…
Pseudotumors
Fig. 1.1 Accessory hepatic lobe. The accessory lobe is attached to the liver by a pedicle of fibrovascular tissue Accessory lobes can measure up to 19 cm [2]. They can…
Cholangiocarcinoma
Risk factors for intrahepatic cholangiocarcinoma Viral hepatitis (B and C) Fibrocystic diseases • Autosomal dominant polycystic kidney and liver disease • Choledochal cyst • Caroli’s disease • Congenital hepatic fibrosis…
Malignant Mesenchymal Tumors
Fig. 11.1 Epithelioid hemangioendothelioma, gross. A liver explant showing multiple tumor nodules ranging from a few millimeters to several centimeters 11.1.4 Microscopic Findings Microscopically, epithelioid hemangioendothelioma is characterized by individual…
Hematolymphoid Lesions
Fig. 12.1 The hemophagocytic syndrome. The sinusoids show prominent benign histiocytes containing phagocytized erythrocytes 12.2 B-Cell Lymphomas 12.2.1 Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma and Mantle Cell Lymphoma 12.2.1.1 Definition Chronic…
Malignant Pediatric Liver Tumors
Epithelial tumors Hepatocellular: Hepatoblastoma Epithelial Pure fetal with low mitotic activity Fetal, mitotically active Pleomorphic, poorly differentiated Embryonal Small cell undifferentiated INI-1 negative INI-1 positive Mixed epithelial (any or all…
Cholangiocarcinoma Precancerous Lesions
Fig. 9.1 Mucinous cystic neoplasm. This cross-section shows a multilocular cyst filled with thin watery fluid Fig. 9.2 Mucinous cystic neoplasm. This mucinous cystic neoplasm shows a multilocular cyst with…
Benign Biliary Tumors
Fig. 5.1 Ciliated hepatic foregut cyst. The wall of ciliated hepatic foregut cyst has four layers: ciliated epithelium, subepithelial connective tissue, smooth muscle, and fibrous stroma Fig. 5.2 Ciliated hepatic…
