Abstract Intestinal failure (IF) is defined as the end result of any gastrointestinal disorder in which functional intestinal mass is insufficient to allow adequate growth, hydration, and electrolyte balance in…
Abstract Elevation of the serum bilirubin level is a common finding during the first week of life. This can be a transient phenomenon that resolves spontaneously, or it can signify…
Abstract Inherited cholestasis of hepatocellular origin has long been described in the neonate or during the first year of life [1]. Many of these infants were categorized as having idiopathic…
Abstract Biliary atresia and related disorders of the biliary tract, such as choledochal cysts, must be considered in the differential diagnosis of prolonged conjugated hyperbilirubinemia in the newborn (neonatal cholestasis)….
Abstract Neonatal hepatitis refers to a heterogeneous group of disorders that result in a somewhat similar morphologic change in the liver of an infant younger than three months of age…
Abstract When first encountering an infant or child with cholestatic liver disease, it is essential that diagnostic evaluation be conducted promptly in order to recognize disorders amenable either to specific…
Abstract Jaundice sometimes appears at birth, indicated by the dark yellow color of the countenance and arising from obstructions of the liver. Cases are generally incurable. Chapter 8 Approach to…
Abstract A portal system is one, which by definition, begins and ends with capillaries. The major portal system in humans is one in which the capillaries originate in the mesentery…
Abstract The word “cirrhosis” comes from the Greek kirrhos, meaning yellowish, tawny, and describes the gross pathology of the diseased liver. Since the late 1980s, however, clinicians have used the…
Abstract The liver is a multifunctional organ that is involved in a number of critical excretory, synthetic and metabolic functions. Biochemical assessment of these functions in children is undertaken by…
