Other Rare Lesions
, Adele Taibbi1 and Massimo Midiri1 (1) Department of Radiology, University Hospital, Palermo, Italy 5.1 Angiomyolipoma The angiomyolipoma (AML) is a mixed mesenchymal tumor that rarely arises in the liver, being…
Fatty Liver, Pseudolesions
, Adele Taibbi1 and Massimo Midiri1 (1) Department of Radiology, University Hospital, Palermo, Italy Diffuse fatty infiltration is a common imaging finding due to the abnormal accumulation of lipids within hepatocytes….
Impact of European Guidelines on CEUS
, Adele Taibbi1 and Massimo Midiri1 (1) Department of Radiology, University Hospital, Palermo, Italy As reported in the guidelines and good clinical practice recommendations for contrast-enhanced ultrasound (CEUS) in the liver,…
Introduction
, Adele Taibbi1 and Massimo Midiri1 (1) Department of Radiology, University Hospital, Palermo, Italy 1.1 General Overview Thanks to the most recent technological innovations, the ability of grayscale ultrasound (US) in…
Pathogenesis of NAFLD and NASH
Fig. 4.1 Adipocyte dysfunction in obesity . Adipocytes hypertrophy and enlarge during obesity. This can lead to an imbalance between blood flow and oxygen demand, resulting in hypoxia and cell…
Pathology of Alcoholic and Nonalcoholic Fatty Liver Disease
Fig. 12.1 Features of NAFLD. (a) Zone 3 distribution of steatosis in a case without fibrosis or features of steatohepatitis. Portal areas are indicated with arrowheads. (b) Zone 3 injury…
Animal Models of Alcoholic Liver Disease
1.Heavy and steady ethanol intake 2.Physical and metabolic tolerance to ethanol: achieving high BACs which are tolerated by the model 3.Chronicity of ethanol intake: at least 10~25 % of life…
Epidemiology and Risk Factors for Alcoholic Liver Disease
Fig. 1.1 Conceptual model. As alcoholic liver disease progresses from fatty liver to cirrhosis, the risk of complications increases. Death related to these complications can develop at any stage of…
Genetic Basis of Alcoholic and Nonalcoholic Fatty Liver Disease
Fig. 7.1 NAFLD and AFLD share similar underlying pathogenic mechanisms and a common underlying genetic component. The cartoon depicts the disease progression of NAFLD and AFLD from normal liver to…
Pathogenesis of Alcoholic Liver Disease
Fig. 3.1 Effects of heavy alcohol use on metabolic and signaling pathways leading to increased hepatic fat synthesis. Heavy alcohol use increases hepatic triglyceride content via increased uptake of fatty…
