Abdominal Key

Testicular germ cell cancer is one of the most curable cancers. Most patients are treated during their reproductive years, making infertility a significant quality of life issue after successful treatment….

Key points • Potentially long-term life-threatening complications, including second malignant neoplasms, cardiovascular disease, neurotoxicity and ototoxicity, pulmonary complications, hypogonadism, and nephrotoxicity have accompanied the remarkable successes of testicular cancer treatment….

Retroperitoneal recurrences following retroperitoneal lymph node dissection (RPLND) are rare events and, with few exceptions, should be regarded as either surgical or technical failures, or a result of inappropriate modifications…

Surgery remains an integral component of treating metastatic testicular germ cell tumors outside the retroperitoneum. Defining the role of surgery in extraretroperitoneal (ERP) disease can be challenging because metastases can…

Germ cell tumors of the testis have an overall survival rate greater than 90% as a result of a successful multidisciplinary approach to management. Late relapse affects a subset of…

Key points • Patients with persistently elevated serum tumor markers should be monitored for marker kinetics and evaluated for nonviable cancer causes of marker elevation. • Desperation postchemotherapy retroperitoneal lymph…

The rate of diagnosis of germ cell tumors has remained fairly constant. By the International Germ Cell Cancer Consensus Classification, roughly 60% of all metastatic germ cell tumors are classified…

Retroperitoneal lymph node dissection after chemotherapy has a proved role in the staging and treatment of metastatic testicular cancer. Complete removal of all postchemotherapy residual masses in nonseminomatous germ cell…

Key points • Through a better understanding of lymphatic dissemination in testicular germ cell tumors, modifications in the boundaries of dissection have improved the long-term morbidity of retroperitoneal lymphadenectomy (RPLND)…