Chapter 4 – Acute Liver Failure in Children
Abstract Pediatric acute liver failure (PALF) is not a single diagnosis. Rather, PALF is a complex, rapidly progressive clinical syndrome that is the final common pathway for many disparate conditions;…
Chapter 3 – Mechanisms of Bile Formation and the Pathogenesis of Cholestasis
Abstract Bile formation and flow is an essential physiological function. Adequate bile flow is necessary for innumerable daily functions including digestion, metabolism, growth, development, toxin elimination and adaptation to liver…
Chapter 2 – Functional Development of the Liver
Abstract The liver attains its highest relative size at about 10% of fetal weight at the ninth week of gestation. Early in gestation the liver is the primary site for…
Chapter 1 – Liver Development
Abstract The essential liver endocrine and exocrine functions require a precise spatial arrangement of the repeated hepatic lobule consisting of the central vein, portal vein, hepatic artery, intrahepatic bile duct…
