NEPHROLOGY

and Chronic Kidney Disease

Oct 20, 2020 by in NEPHROLOGY Comments Off on and Chronic Kidney Disease

Fig. 6.1 Prevalence of chronic kidney disease by age group in the National Health and Nutrition Examination Survey (NHANES) for 1988–1994 and 1999–2004. (Reproduced with permission from Coresh et al….

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in Chronic Kidney Disease

Oct 20, 2020 by in NEPHROLOGY Comments Off on in Chronic Kidney Disease

Pharmacokinetic process Changes in hemodialysis Absorption Increased absorption mediated by: • Paracellular leakage • Decreased efflux transporter activity • Decreased P450 activity Distribution Increased free drug concentration mediated by: • Decreased albumin concentration • Uremic…

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System Disorders in Chronic Kidney Disease: Neurocognitive Dysfunction, Depression, and Sleep Disorder

Oct 20, 2020 by in NEPHROLOGY Comments Off on System Disorders in Chronic Kidney Disease: Neurocognitive Dysfunction, Depression, and Sleep Disorder

Domains Tests Global cognition Mini-Mental State Exam (MMSE) The Modified Mini-Mental State (3MS) Montreal Cognitive Assessment (MoCA) The Kidney Disease Quality of Life (KDQOL) cognitive function subscale (KDOQL-SF) Mini-cog Memory…

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Deficiency and Infection in Chronic Kidney Disease

Oct 20, 2020 by in NEPHROLOGY Comments Off on Deficiency and Infection in Chronic Kidney Disease

Uremic toxins Effects on immune cells Low molecular weight (LMW) toxins Phenylacetic acid (PAA) Macrophages: inducible nitric oxide synthase PMNLs: oxidative burst, phagocytosis, increased integrin expression, and decreased apoptosis Dinucleoside…

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Kidney Disease-Mineral and Bone Disorder, Vitamin D Deficiency, and Secondary Hyperparathyroidism

Oct 20, 2020 by in NEPHROLOGY Comments Off on Kidney Disease-Mineral and Bone Disorder, Vitamin D Deficiency, and Secondary Hyperparathyroidism

!DOCTYPE html> © Springer Nature Singapore Pte Ltd. 2020J. Yang, W. He (eds.)Chronic Kidney Diseasedoi.org/10.1007/978-981-32-9131-7_11 11. Chronic Kidney Disease-Mineral and Bone Disorder, Vitamin D Deficiency, and Secondary Hyperparathyroidism Mingxia Xiong1   (1) Centre for Kidney…

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of Chronic Kidney Disease

Oct 20, 2020 by in NEPHROLOGY Comments Off on of Chronic Kidney Disease

Fig. 2.1 Schematic presentation for cellular events involved in the progression of chronic kidney disease 2.2 Glomerulosclerosis Each normal glomerulus is a tuft of small blood vessels called capillaries situated…

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in Chronic Kidney Disease

Oct 20, 2020 by in NEPHROLOGY Comments Off on in Chronic Kidney Disease

Fig. 10.1 Flowchart for the evaluation of anemia in patients with chronic kidney disease. TIBC total iron-binding capacity; TSAT transferrin saturation; SF serum ferritin; ESA erythropoiesis-stimulating agent Key Messages KDIGO…

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Disease in Chronic Kidney Disease

Oct 20, 2020 by in NEPHROLOGY Comments Off on Disease in Chronic Kidney Disease

Traditional risk factors Nontraditional risk factors Hemodynamic factors Metabolic factors Old age Volume overload Proteinuria Male sex Anemia Chronic inflammatory state Menopause Arteriovenous fistula Malnutrition Smoking habit Arteriosclerosis Disorders of…

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in Chronic Kidney Disease

Oct 20, 2020 by in NEPHROLOGY Comments Off on in Chronic Kidney Disease

Classification of aspects Aspects of management Medications • Selection and adjustment of immunosuppressant and other medications for CKD (Table 5.2) • Low-molecular-weight heparin, which is recommended to prevent thrombosis in patients with…

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