NEPHROLOGY

Role of Proteinuria in the Progression of Renal Disease

Jun 6, 2019 by in NEPHROLOGY Comments Off on Role of Proteinuria in the Progression of Renal Disease

Introduction Chronic progressive nephropathies, independent of the type of the initial insult, have in common persistently high levels of urinary protein excretion, chronic tubulointerstitial lesions, and glomerular sclerosis. It has…

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Autosomal Dominant Polycystic Kidney Disease

Jun 6, 2019 by in NEPHROLOGY Comments Off on Autosomal Dominant Polycystic Kidney Disease

Autosomal dominant polycystic kidney disease (ADPKD) (MIM 173900) is a systemic disorder characterized by age-dependent occurrence of bilateral, multiple renal cysts as well as a variety of extrarenal manifestations. The…

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Pathophysiology of Acute Kidney Injury

Jun 6, 2019 by in NEPHROLOGY Comments Off on Pathophysiology of Acute Kidney Injury

This chapter focuses on the pathophysiological principles of Acute Kidney Injury (AKI), with special emphasis on the structural, cellular and molecular alterations occurring in ischemic, nephrotoxic and septic AKI. Changing…

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Genetic Abnormalities in Glomerular Function

Jun 6, 2019 by in NEPHROLOGY Comments Off on Genetic Abnormalities in Glomerular Function

This chapter discusses recent advances in the understanding of genetic kidney diseases that primarily involve the glomerulus. The chapter is organized according to the site or mechanism of the primary…

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Ischemic Renal Disease

Jun 6, 2019 by in NEPHROLOGY Comments Off on Ischemic Renal Disease

The intrinsic ability of the kidney to regulate renal blood flow and glomerular filtration rate (GFR) over a wide range of perfusion pressures has fascinated physiologists for decades. These adaptive…

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Renal Failure in Cirrhosis

Jun 6, 2019 by in NEPHROLOGY Comments Off on Renal Failure in Cirrhosis

Renal failure is a common complication of patients with advanced cirrhosis. The most common causes of renal failure in cirrhosis are those related to bacterial infections (with or without septic…

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