A subset of patients with chronic constipation, up to 50% at tertiary centers, have difficult defecation, which can be suspected by clinical features and confirmed by anorectal tests. Symptoms of…
Chronic intestinal pseudo-obstruction (CIPO) is today a significant indication for home parenteral nutrition (HPN) in both adults and children. CIPO refers to a heterogeneous group of disorders characterized by symptoms…
The population of the Western world is abundantly exposed to food. Together with the introduction of fast food, this situation has contributed to an exponential increase in morbid obesity. Similarly,…
Functional gastrointestinal disorders range from highly prevalent, but generally benign conditions, eg, functional dyspepsia and irritable bowel syndrome, to rare and potentially life-threatening diseases, eg, intestinal pseudo-obstruction syndromes. The term…
Down Syndrome Down syndrome (DS) is the most common chromosomal abnormality occurring in humans. In Europe, DS accounts for 8% of all registered cases of congenital anomalies. Throughout the world,…
Gastrointestinal (GI) symptoms occur commonly in patients with cancer and may reflect dysfunction throughout the gut ( Box 1 ). Many potential causes exist for these symptoms including GI dysmotility….
As populations age, the prevalence of neurologic disease in the community continues to increase, and consultations relating to gastrointestinal motility problems in the patient afflicted with a neurologic disorder become…
Gastrointestinal motility can be markedly deranged in critical illness. This can have a number of important clinical sequelae—the most obvious of which is impaired delivery of enteral nutrition, which can…
This issue of Gastroenterology Clinics of North America is focused on challenges faced in everyday clinical practice. Thus rather than reviewing the evolving research literature that details the many experimental…
Gastrointestinal motility disorders affect the neuromuscular functions needed for movement of contents through the gastrointestinal tract. This definition excludes strictures and other mechanical causes for impaired passage from the concept…
