Fig. 5.1 Diagnostic value of microbiome indices in type 2 diabetes and primary sclerosing cholangitis. Area under the receiver operating characteristic curve to identify type 2 diabetes (left) and primary…
Fig. 14.1 (a) MRC images suspicious for a dominant stenosis in the mid bile duct (arrow). (b) Follow-up ERCP showed no evidence of stenosis in the bile duct (arrow) The…
Fig. 13.1 US of a 24-year-old female with PSC. (a) US shows anechoic bile in mildly dilated extrahepatic bile duct, mucosal irregularity, and diffuse bile duct wall thickening (arrow). (b)…
Normal Activated Senescent/SASP Malignant Markers Phenotypic characteristic Markers Phenotypic characteristic Markers Phenotypic characteristic Markers Phenotypic characteristic AE2 Transports intracellular Cl−/HCO3 − αvβ6 integrin Induces proliferation and migration SA-β-Gal Large, flat…
Chromosome Plausible risk gene Study 1 MMEL1, TNFRSF14 Folseraas et al. (2012) [56] 2 BCL2L11 Melum et al. (2011) [59] 2 CD28, CTLA4 Liu et al. (2013) [27] 2 CCL20…
Study Country Cohort N. of patients IgG4-SC N (%) AIP N (%) Kanno et al. [43] Japan AIP 91 8 311 (33.8) 918 (100) Ghazale et al. [26] USA IgG4-SC…
Features Classical AID PSC Autoantigen(s) Yes Possibly Autoantibody Yes, pathogenetic Yes, biomarker Age Children and adults Children and adults Gender predilection Female > male Male > female Genetic factors HLA,…
Region Study period Number of cases Incidencea Prevalenceb Reference Northern Europe Norway 1986–1995 17 1.3 8.5 [9] Sweden 1992–2005 199 1.22 16.2 [8] Netherlands 2000–2007 519 0.5 6.0 [12] UK…
Fig. 3.1 Absolute cumulative risk for colorectal dysplasia or cancer over time among patients with UC and those with PSC-UC [1] Given the apparent increased incidence of colorectal neoplasia in…
and James R. BurtonJr.1 (1) University of Colorado Hospital, Anschutz Outpatient Pavilion, 7th Floor, Transplant Center, 1635 Aurora Court, B154, Aurora, CO 80045, USA James R. BurtonJr. Email: James.Burton@UCDenver.edu KeywordsCholangiocarcinomaHepatocellular carcinomaGallbladder carcinoma Technical…
