Role of Endoscopy in GERD
Endoscopy is commonly performed for the diagnosis and management of gastroesophageal reflux disease (GERD). Endoscopy allows the physician to evaluate esophageal mucosa for evidence of esophagitis and Barrett esophagus, to…
Symptom Predictability in Gastroesophageal Reflux Disease and Role of Proton Pump Inhibitor Test
There are problems with the definition, assessment, and measurement of gastroesophageal reflux disease (GERD). The Reflux Disease Questionnaire and the GERD questionnaire are patient-reported outcome (PRO) measures for use in…
Pathophysiology of Gastroesophageal Reflux Disease
Gastroesophageal reflux disease (GERD) is one of the most common digestive diseases in the Western world, with typical symptoms, such as heartburn, regurgitation, or retrosternal pain, reported by 15% to…
Epidemiology of Gastroesophageal Reflux Disease
The prevalence of gastroesophageal reflux disease (GERD) symptoms increased approximately 50% until the mid-1990s, when it plateaued. The incidence of complications related to GERD including hospitalization, esophageal strictures, esophageal adenocarcinoma,…
Forthcoming Issues
Forthcoming Issues June 2014 Eosinophilic Esophagitis Ikuo Hirano, Editor September 2014 Upper GI Bleeding Ian Gralnek, Editor December 2014 Biologics of IBD Edward Loftus, Editor Recent Issues December 2013 Disorders…
What’s New in Gastroesophageal Reflux Disease for 2014
Joel E. Richter, MD, FACP, MACG, Editor It is my pleasure to present you with this issue of Gastroenterology Clinics of North America . The issue focuses on a common…
Gastroesophageal Reflux Disease
Gary W. Falk, MD, MS, Consulting Editor Gastroesophageal reflux disease (GERD) remains one of the most common problems encountered in gastrointestinal clinical practice with over 8 million patient visits in…
Eosinophilic Esophagitis
Twenty years have passed since eosinophilic esophagitis was first recognized as a new and distinct entity. Current treatment modalities for eosinophilic esophagitis include the “3 Ds”: drugs, allergen avoidance with…
Steroids in Pediatric Eosinophilic Esophagitis
Swallowed fluticasone and oral viscous budesonide are effective first-line therapies for eosinophilic esophagitis in children. Side effects are minimal without evidence of Cushing syndrome, as seen in treatment with systemic…
Dietary Treatment of Eosinophilic Esophagitis
Emerging evidence supports impaired epithelial barrier function as the key initial event in the development of eosinophilic esophagitis (EoE) and other allergic diseases. Symptom resolution, histologic remission, and prevention of…
