Chapter Outline DISORDERS OF CALCIUM HOMEOSTASIS, 601 Whole-Body Calcium Homeostasis, 601 Hypercalcemia, 602 Hypocalcemia, 612 DISORDERS OF MAGNESIUM HOMEOSTASIS, 618 Hypomagnesemia and Magnesium Deficiency, 618 Hypermagnesemia, 625 DISORDERS OF PHOSPHATE…
Chapter Outline INDEPENDENT REGULATION OF WATER AND SALT EXCRETION, 258 CRITICAL ROLE OF PARALLEL ORGANIZATION OF STRUCTURES IN THE RENAL MEDULLA TO URINARY CONCENTRATING AND DILUTING PROCESS, 259 Renal Tubules,…
Chapter Outline VASOPRESSIN—THE ANTIDIURETIC HORMONE, 282 THE TYPE 2 VASOPRESSIN RECEPTOR—A G PROTEIN–COUPLED RECEPTOR, 282 Interaction of Type 2 Vasopressin Receptor with Heterotrimeric G Proteins and β-Arrestin, 282 Fate of…
Chapter Outline GROSS FEATURES, 42 THE NEPHRON, 44 Renal Corpuscle, 45 Endothelial Cells, 46 Glomerular Basement Membrane, 48 Visceral Epithelial Cells, 49 Mesangial Cells, 51 Parietal Epithelial Cells, 52 Peripolar…
Chapter Outline GENERAL INTRODUCTION TO ALDOSTERONE AND MINERALOCORTICOID RECEPTORS, 304 ALDOSTERONE SYNTHESIS, 305 MECHANISMS OF MINERALOCORTICOID RECEPTOR FUNCTION AND GENE REGULATION, 306 Mineralocorticoid Receptor Function as a Hormone-Regulated Transcription Factor:…
Chapter Outline BICARBONATE REABSORPTION, 234 Proximal Tubule, 234 Loop of Henle, 238 Distal Convoluted Tubule, 238 Collecting Duct, 239 BICARBONATE GENERATION, 246 Titratable Acid Excretion, 246 Organic Anion Excretion, 247…
Chapter Outline RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM, 325 Classical Renin-Angiotensin-Aldosterone System, 326 Expanded Renin-Angiotensin-Aldosterone System: Enzymes, Angiotensin Peptides, and Receptors, 331 Renin-Angiotensin-Aldosterone System in Kidney Pathophysiology, 334 ENDOTHELIN, 335 Structure, Synthesis, and Secretion…
Chapter Outline THERMODYNAMIC APPROACH TO METABOLISM AND TRANSPORT, 123 Thermodynamic Analysis of Kidney Function, 123 Application of the Laws of Thermodynamics to Kidney Function, 123 ENERGY AND THE SODIUM PUMP,…
Chapter Outline MAMMALIAN KIDNEY DEVELOPMENT: EMBRYOLOGY , 2 Development of the Urogenital System, 2 Development of the Metanephros, 3 Development of the Nephron, 4 The Nephrogenic Zone, 5 Branching Morphogenesis:…
Chapter Outline BIOLOGIC FUNCTIONS OF PODOCYTES, 112 ULTRASTRUCTURAL AND MOLECULAR ANATOMY OF PODOCYTES REQUIRED FOR NORMAL STRUCTURE AND FUNCTION, 113 Structure, 113 Slit Diaphragm Proteins, 113 Cytoskeleton, 113 GLOMERULAR DISEASES…
