Abstract The population of individuals with kidney failure requiring renal replacement therapy in the United States and around the world continues to grow. The optimal timing for the initiation of…
Abstract A number of nutrition-related and catabolism-related complications arise with the loss of kidney function. These abnormalities are collectively termed protein-energy wasting (PEW) syndrome and have important consequences on patients’…
Outline Sleep in Chronic Kidney Disease, 224 Sleep in End-Stage Kidney Disease, 226 Sleep in Hemodialysis, 227 Sleep in Peritoneal Dialysis, 229 Sleep in Pediatric Chronic Kidney Disease, 231 Sleep…
Abstract Uremia is a clinical syndrome with a wide range of signs and symptoms. It arises with advanced kidney failure and is characterized by the accumulation of numerous organic chemicals…
Abstract Systemic inflammation is a common complication that contributes to the abysmal outcomes in patients with advanced chronic kidney disease (CKD). It is caused by a range of factors associated…
Abstract Patients with chronic kidney disease (CKD) are very complex with regard to disease, comorbidity, number of medications, and dosage regimens. In this chapter we discuss (1) the implications of…
Abstract While living with CKD poses many of the same psychological challenges as many other chronic illnesses, the high treatment burden, chronicity, and unique physiological demands of the illness expose…
Abstract Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in patients with chronic kidney disease (CKD). The increased risk of CVD begins during the earlier stages of…
Abstract The kidney plays a fundamental role in the metabolism and catabolism of vitamin D. Deficiency of vitamin D, both 25-hydroxyvitamin D and 1,25-dihyroxyvitamin D, is common among adults and…
Abstract Abnormalities in mineral metabolism occur early in the course of chronic kidney disease, even as early as stage 2, and progress as kidney function worsens. The progression of kidney…
