Management of Sickle Cell Anemia
Fig. 13.1 Red blood cells of a patient with sickle-cell disease. Left: Oxygenated. Right: Deoxygenated. The shape of the cells when deoxygenated causes them to break easily. [Courtesy of Dr….
Post-Transplant Anemia
(a) Blood loss anemia Intraoperative blood loss Repeated blood draws—phlebotomy Gastrointestinal Menstrual blood losses (b) Decreased RBC production Decreased effective production Iron deficiency—absolute or functional Folate deficiency—medications Pure red cell…
Anemia in Malignancy
Grade Symptom severity Hemoglobin values 0 Within normal limits 12.0–16.0 g/dL for women and 14.0–18.0 g/dL for men 1 Mild 10 g/dL to levels within normal limits 2 Moderate 8.0–10.0 g/dL 3 Serious/severe 6.5–7.9 g/dL…
Current and Novel Drugs for Management of Anemia
Fig. 5.1 Normal erythropoiesis. The hematopoietic stem cell (HSC), once committed, differentiates into the blast-forming units—erythroid (BFU-E) that in turn differentiates into the colony-forming unit—erythroid (CFU-E). The proerythroblast (Pro-EB), the…
Anemia in Liver Disease
Acute blood loss anemia (portal hypertension-related) Esophageal varices Gastric varices Rectal varices Chronic blood loss anemia Portal hypertensive gastropathy Portal hypertensive enteropathy Portal hypertensive colopathy Gastric-antral vascular ectasia Acute hemolytic…
Disease State: Kidney Disease
Method Equation Cockcroft-Gault [(140—Age in years) × (Weight in kg) × (0.85 if female)]/(72 × Scr in mg/dL) MDRD 186 × (Scr)−1.154 × (Age)−0.203 × (0.742 if female) × (1.212 if African American) CKD-EPI A × (Scr/B)C × (0.993)Age A: African American female = 166; African American male = 163;…
Anemia of Chronic Kidney Disease
Oral agents Intravenous agents Most common agents Ferrous fumarate Ferric gluconate Ferrous gluconate Ferumoxytol Ferrous sulfate Iron sucrose Polysaccharide-iron complex Side effects Gastrointestinal (metallic taste, flatulence, constipation, diarrhea, abdominal…
Special Populations with Anemia: Anemia in the Pediatric Patient
Age Hemoglobin (g/dL Mean corpuscular volume (fL) Mean Lower limita Mean Lower limita Birth (cord blood) 16.5 13.5 108 98 1–3 days (capillary) 18.5 14.5 108 95 1 week 17.5 13.5 107…
Nutritional Anemia in Adults and in Elderly Patients
Etiology Prevalence (%) Chronic inflammation (chronic disease) 23.0 Iron deficiency 18 Renal failure 9 Liver disease and endocrine disease (chronic disease) 7 Posthemorrhagic 7 Folate deficiency 6 Myelodysplasia 5 Vitamin…
The Complex Relationships Between Iron Regulation, Obesity, and Anemia
© Springer Science+Business Media LLC 2018Robert Provenzano, Edgar V. Lerma and Lynda Szczech (eds.)Management of Anemiahttps://doi.org/10.1007/978-1-4939-7360-6_10 10. The Complex Relationships Between Iron Regulation, Obesity, and Anemia Stephen Z. Fadem1 (1) Department of Medicine, Baylor College of Medicine, 6624…
