There are problems with the definition, assessment, and measurement of gastroesophageal reflux disease (GERD). The Reflux Disease Questionnaire and the GERD questionnaire are patient-reported outcome (PRO) measures for use in…
Gastroesophageal reflux disease (GERD) is one of the most common digestive diseases in the Western world, with typical symptoms, such as heartburn, regurgitation, or retrosternal pain, reported by 15% to…
The prevalence of gastroesophageal reflux disease (GERD) symptoms increased approximately 50% until the mid-1990s, when it plateaued. The incidence of complications related to GERD including hospitalization, esophageal strictures, esophageal adenocarcinoma,…
Forthcoming Issues June 2014 Eosinophilic Esophagitis Ikuo Hirano, Editor September 2014 Upper GI Bleeding Ian Gralnek, Editor December 2014 Biologics of IBD Edward Loftus, Editor Recent Issues December 2013 Disorders…
Joel E. Richter, MD, FACP, MACG, Editor It is my pleasure to present you with this issue of Gastroenterology Clinics of North America . The issue focuses on a common…
Gary W. Falk, MD, MS, Consulting Editor Gastroesophageal reflux disease (GERD) remains one of the most common problems encountered in gastrointestinal clinical practice with over 8 million patient visits in…
Twenty years have passed since eosinophilic esophagitis was first recognized as a new and distinct entity. Current treatment modalities for eosinophilic esophagitis include the “3 Ds”: drugs, allergen avoidance with…
Swallowed fluticasone and oral viscous budesonide are effective first-line therapies for eosinophilic esophagitis in children. Side effects are minimal without evidence of Cushing syndrome, as seen in treatment with systemic…
Emerging evidence supports impaired epithelial barrier function as the key initial event in the development of eosinophilic esophagitis (EoE) and other allergic diseases. Symptom resolution, histologic remission, and prevention of…
Topical steroid therapy has been used to treat eosinophilic esophagitis (EoE) for more than 15 years. We review the treatment trials of topical steroid therapy in adult patients with EoE. Currently,…
