Abdominal Key

Parasites in the Liver Bobbi S. Pritt, MD, MSc 9.1 INTRODUCTION Parasites are an important cause of infections in the liver and biliary tract and are responsible for significant morbidity…

Granulomatous Liver Disease Vishal S. Chandan, MD Tsung-Teh Wu, MD, PhD 11.1 INTRODUCTION Granulomas are localized collections of macrophages and other inflammatory cells, such as lymphocytes, that usually develop in…

Viral Hepatitis Roger K. Moreira, MD Douglas A. Simonetto, MD 8.1 GRADING AND STAGING OVERVIEW In a fashion somewhat analogous to tumor pathology—where grade refers to features that reflect disease…

Other Infections of the Liver Michael S. Torbenson, MD 10.1 INTRODUCTION This chapter discusses nonviral and nonparasitic infections of the liver, though infections that are primarily granulomatous are discussed with…

The Almost Normal Liver Biopsy Michael S. Torbenson, MD 7.1 OVERVIEW Liver biopsies can sometimes be almost normal on histological examination, even when performed for clinical indication. The clinical indication…

Electron Microscopy Taofic Mounajjed, MD 5.1 INTRODUCTION The rise of immunohistochemical, molecular, and serologic techniques in pathology over the past decades has somewhat sidelined certain diagnostic uses of the more…

Basic Patterns of Injury in Medical Liver Pathology Roger K. Moreira, MD A pattern of injury represents individual histologic findings that cluster into a meaningful and recognizable histologic pattern. Identification…

The Language of Liver Pathology: Definitions of Key Terms Michael S. Torbenson, MD 3.1 INTRODUCTION Like all medical disciplines, liver pathology has its own vocabulary used to describe histological findings….

Immunohistochemistry and Special Stains in Liver Pathology Michael S. Torbenson, MD 4.1 OVERVIEW This chapter considers special stains used in medical liver specimens and is organized into the following sections:…

Gross Processing of Liver Specimens Roger K. Moreira, MD 2.1 GROSS ANATOMY Weight The normal human liver varies significantly in size, with an average weight of approximately 1,500 g (ranging…