Topical Mesalamine
Fig. 8.1 Distribution of 5-ASA suppository in a patient with ulcerative proctitis. 99mTc-labeled 5-ASA suppository was given to a patient with refractory ulcerative proctitis. The medication spread to the sigmoid…
The Natural History of Ulcerative Colitis
Fig. 3.1 Graphical representation of the disease activity in 600 UC patients in years 3–7 after diagnosis. 57 % had intermittent activity of which 28 % had a relapse in…
Management of Steroid-Dependent and Steroid-Refractory Ulcerative Colitis
Therapeutic outcome Definition Response to corticosteroids Clinical improvement after treatment with high-dose oral steroids (40–60 mg prednisone or equivalent) within 30 days or clinical improvement after treatment with high-dose intravenous…
Oral Mesalamine
Fig. 6.1 The potential role of mesalamine in the current treatment algorithm for UC In the present chapter, we will review the pharmacology, mechanisms of action, and effectiveness of oral…
Treatment of Ulcerative Proctitis
Medication Mesalamine DR (Asacol, Asacol HD) 800 mg DR, 1–2 tabs TID Mesalamine ER (Apriso, currently only approved for maintenance) 0.375 g ER, 4 tabs QAM Mesalamine ER (Pentasa) 250/500…
Management of Irritable Bowel Syndrome in the Patient with Ulcerative Colitis
Gassy foods Vegetables (raffinose, soluble fiber) Artichokes Asparagus Beans Broccoli Brussels sprouts Cabbage Carrots Cauliflower Celery Cucumbers Green peppers Lentils Onions Peas Potatoes Radishes Shallots Scallions Fruits (fructose or sorbitol)…
Parenteral Nutrition Use in Ulcerative Colitis
Study Remission rate Follow-up Gimpel/Schilling [1] ? 72 days Truelove/Jewell [3] 60/100 (60 %) Up to 3 years Dean et al. [5] 1/5 (20 %) Same admission Reilly et al….
Mimics of Ulcerative Colitis
32. Saebo A, Vik E, Lange OJ, Matuszkiewicz L. Inflammatory bowel disease associated with Yersinia enterocolitica O:3 infection. Eur J Intern Med. 2005;16:176–82.PubMedCrossRef 33. Kallinowski F, Wassmer A, Hofmann MA,…
Assessment of Disease Activity in Ulcerative Colitis
Type of index Index main name akaa Abbreviation Reference Symptoms Partial Mayo score [13] Simple clinical colitis activity index SCCAI [14] Modified Truelove and Witts index Lichtiger score MTWSI [15]…
Medical Therapy in the Preoperative and Postoperative Patient
Minor surgical stress (hernia repair) Moderate surgical stress (cholecystectomy, colectomy) Major surgical stress (cardiac surgery, hepatobiliary surgery) No HPA axis suppression: Continue usual daily glucocorticoid dose Continue usual daily…
