Living Donor Nephrectomy
Fig. 18.1 Vein graft for living kidney transplantation and back table of an artery graft for living kidney transplantation 18.2.2 Retroperitoneal The donor is placed in the lateral decubitus position…
Live Donor Evaluation
History and examination Instrumental investigations Microbiological screening Laboratory investigations Immunological investigations Family history Chest radiograph HBV Blood count and coagulation Blood group Pathological history Electrocardiogram HCV Urea, creatinine, serum uric…
Indications and Timing
Fig. 15.1 Natural history of renal disease To determine the timing, i.e., when to proceed to transplantation, a distinction must be made between theory and practice. In theory, transplant should…
Postoperative Technical Complications
Fig. 12.1 Percutaneous transhepatic cholangiography showing typical findings of intrahepatic biliary dilatation and stenosis, “cast syndrome,” due to posttransplant hepatic thrombosis. Early surgical revascularization was performed, but the patient required…
Anaesthetic and Perioperative Management for Liver Transplantation
Hepatic Renal electrolyte glucose Cardiovascular Pulmonary Neurologic Haematologic Decreased metabolic function Acute kidney injury Vasodilated state Aspiration risk Hepatic encephalopathy Bleeding and thrombosis Decreased gluconeogenesis Hepatorenal syndrome Hyperdynamic cardiac function…
Liver Procurement
Category Description I Dead on arrival: corneas, heart valves, skin, bone, etc., can be recovered since there are no immediate time constraints to minimize tissue injury and there is no…
Transplantation Immunology
Fig. 1.1 Structure of mTOR inhibitors, everolimus (left), and sirolimus (right). Everolimus differs from sirolimus due to the addition of a 2-hydroxyethyl group at C40 Table 1.1 mTOR inhibitors –…
Indications for Liver Transplantation
Acetaminophen-induced ALF Nonacetaminophen ALF Arterial pH <7.3 irrespective of grade of encephalopathy or INR >6.5 (PT >100 s), irrespective of grade of encephalopathy PT >100 s Or any 3 of…
Infection Complications After Abdominal Organ Transplantation
Greater infectious risk Critical illness entering transplantation Prior colonization with antimicrobial-resistant pathogens Induction therapy – lymphocyte depletion High-dose corticosteroids Plasmapheresis (not well studied) High rejection risk (HLA mismatch desensitization) Early…
Medical Disease After Abdominal Solid Organ Transplantation and the Risk of Solid and Hematologic Malignant Tumor After Transplantation
Adverse effect Cyclosporine Tacrolimus Steroids Aza Mycophenolate mofetil Sirolimus-everolimus Arterial hypertension +++ ++ +++ − − + Hyperglycemia − + +++ − − − Hyperlipidemia ++ + ++ − −…
