Chapter Outline Introduction Acute Pancreatitis Chronic Pancreatitis Confirming a Diagnosis Alcoholic Pancreatitis Genetics of Pancreatitis Trypsinogen Mutations SPINK1 Mutations CFTR Mutations Hereditary Pancreatitis Pancreatic Divisum Autoimmune Pancreatitis Paraduodenal Pancreatitis (“Groove”…
Chapter Outline Introduction Sampling Gallbladder Specimens Gallbladder Tumoral Intraepithelial Neoplasms Intracholecystic Papillary-Tubular Neoplasms Mucinous Cystic Neoplasms Nontumoral Preinvasive Lesions: Dysplasia and Carcinoma In Situ Adenocarcinoma Papillary Carcinomas Mucinous Carcinoma Adenosquamous…
Chapter Outline Introduction Helpful Diagnostic Tips Identification of Major Pattern of Injury Predominantly Portal Inflammation Ductular Reaction Steatosis Prominent Lobular Inflammation Pigments in the Liver Fibrosis (and Cirrhosis) Diagnosis of…
Chapter Outline Introduction Laboratory and Histologic Changes of the Liver in Pregnancy Intrahepatic Cholestasis of Pregnancy Acute Fatty Liver of Pregnancy Preeclampsia and Eclampsia HELLP Syndrome Hepatic Rupture Hyperemesis Gravidarum…
Chapter Outline Introduction Anatomic and Histologic Considerations Classification of Ampullary Tumors Preinvasive Neoplasms Adenomas of the Ampullary Duodenum Intraampullary Papillary-Tubular Neoplasms Flat Dysplasia Invasive Adenocarcinomas Uncommon Carcinomas Staging of Ampullary…
Chapter Outline Liver Biopsy Specimens Specimen Handling Normal Microanatomy of the Liver Interpretation of Liver Biopsies Liver Resection Specimens Partial Hepatectomies Liver Explants Routine and Special Stains Immunohistochemistry Electron Microscopy…
Chapter Outline Introduction Autoimmune Hepatitis Primary Biliary Cirrhosis Primary Sclerosing Cholangitis Overlap Syndromes Immunoglobulin G4–Associated Cholangitis Secondary Sclerosing Cholangitis Ischemic Cholangitis Miscellaneous Ductopenic Syndromes Obstructive Cholangitis Introduction The three most…
Chapter Outline Approach to Evaluating Colitis Normal Versus Abnormal Acute Versus Chronic Colitis Ulcerative Colitis Crohn’s Colitis Chronic Inflammatory Bowel Disease, Unknown Type (Indeterminate Colitis) Dysplasia in Inflammatory Bowel Disease…
Chapter Outline Introduction Benign Hepatocellular Tumors Focal Nodular Hyperplasia Hepatocellular Adenoma Use of Molecular Diagnostics Hepatocellular Carcinoma and Its Precursors Molecular Changes in Hepatocarcinogenesis Precancerous Lesions in Hepatocarcinogenesis Early Hepatocellular…
Chapter Outline Introduction Gastrointestinal Stromal Tumors (GISTs) GIST Syndromes and Succinate Dehydrogenase–Deficient GISTs Tumors of Neural Origin Schwannoma Gangliocytic Paraganglioma Ganglioneuroma and Ganglioneuromatosis Mucosal Perineurioma Mucosal Schwann Cell Hamartoma Granular…