Fig. 5.1 Specificity of 89Zr-trastuzumab for HER2-positive tumors. Coronal 89Zr-trastuzumab, 18F-FDG, and 18F-FLT PET images of athymic nude mice bearing subcutaneous HER2-positive NCI-N87 ( left) and HER2-negative MKN-74 ( right)…
Clinical phase Compound Type of compound Target Study details +/- preliminary findings I MGAH22 mAb HER2 Dose escalation study of MGAH22 in patients with refractory HER2-positive breast cancer and patients…
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