Introduction Although the liver is known to be a somewhat immunotolerant organ, pediatric liver transplantation (LT) would not have reached current success without efficient immunosuppressive drugs. Standard protocols include calcineurin…
Introduction Anesthesia for pediatric liver transplantation is complex, diverse, and challenging. The indications for transplantation and the physiology of children vary from the adult population, making the pediatric service unique….
Introduction Intestinal transplantation (ITx) was first attempted in the 1970s in children with intestinal failure (IF) for whom intravenous nutrition was not available. The early efforts did not meet with…
Liver-Heart Indication Combined heart and liver transplantation (CHLT) is still an evolving procedure, representing only 0.3% of all cardiac transplantation in a Unified Network for Organ Sharing (UNOS) database study…
Whereas isolated liver and kidney transplantations (LTs and KTs, respectively) have become routine procedures for isolated organ failure, combined liver and kidney transplantation (CLKT) is relatively rarely performed worldwide, and…
Liver and hematopoietic stem cell transplantation (HSCT) have established their places in the ever-increasing number of individual indications in their respective fields of modern medicine. However, there is a group…
Introduction The transplantation of ABO-identical or ABO-nonidentical ABO-compatible grafts has for decades been the mainstay of organ transplantation. As post-transplant survival improves and the demand for organ transplants grows, several…
Introduction From the beginning of clinical transplantation, back in the 1950s, clinicians struggled to reconcile the contradictory interests in living-related donor transplantation. Murray and Merrill contributed to identifying the three…
The phenomenal success of pediatric liver transplantation (LT) for the treatment of end-stage liver disease over the last 30 years has changed how we define their optimal outcome. Increasing surgical…
Introduction Optimal preparation for pediatric liver transplantation (PLT) is accepted to be one of the cornerstones of favorable outcomes. Preparation depends on many factors spanning timely referral to emergent management…
