Emerging Systemic and Targeted Therapies
Fig. 10.1 Development of new drugs and regimens in the treatment of pancreatic cancer. Drugs or regimen activity demonstrated in a phase III study. Not all agents are approved by…
Overview of Multimodality Therapy
Setting Study Regimen Goal Opened Borderline resectable ALLIANCE A021101 mFFX—no 5FU bolus—4 cycles, then RT/cape; gemcit postop Accrual rate, toxicity, CR/PR, completion of all therapy, R0/R1 March 2013 Pilot study…
Transpelvic Rectus Abdominis Flap Reconstruction Following Abdominoperineal Resection
Fig. 10.1 Pelvic exenteration Differently to the classic VRAM flap, its variants — the de la Plaza, and Taylor flaps, with a skin island designed differently and higher on the…
Indications for Surgery and Surgical Techniques
Fig. 7.1 Operative view after completion of extended (cylindrical) abdominoperineal resection 7.2 Role of Surgery Obtaining a radical R0 resection is the most important prognostic factor related to improved oncologic…
Imaging Modalities
Study N. of patients Indication (%) Mäkelä et al. [16] 106 9 Bleeker et al. [17] 213 33 Primrose et al. [18] 1202 25 Nakamoto et al. [19] 12 58…
Clinical Presentation and Classifications
Authors Classification Definition Pilipshen et al. (1984) [15] Anatomic pelvic side involved Anastomotic Perianastomotic Pelvic disease without fixation Pelvic disease with fixation Pelvic disease (with or without fixation) presenting through…
Italian Survey on the Surgical Treatment of Locally Recurrent Colorectal Cancer
N. Question Type of response 1 How many patients with LRRC were managed within the MDT of your unit in a 24-month period between January 2013 and December 2014? Range…
Local Failure After Conservative Treatment of Rectal Cancer
Reference LR (%) DFS(%) OS (%) Median FU (months) Local excision You et al. [8] 8.2 93 77 60 Bentrem et al. [9] 15.0 93 89 60 Endreseth et…
Techniques of Urological Reconstruction
© Springer-Verlag Italia 2016Giovanni Maria Romano (ed.)Multimodal Treatment of Recurrent Pelvic Colorectal CancerUpdates in Surgery10.1007/978-88-470-5767-8_9 9. Techniques of Urological Reconstruction Giuseppe Quarto, Raffaele Muscariello, Domenico Sorrentino and Sisto Perdonà1 (1) Urologic Surgical Oncology, Department of Urogynecology, Istituto Nazionale Tumori…
Pain Control and Palliative Treatments
© Springer-Verlag Italia 2016Giovanni Maria Romano (ed.)Multimodal Treatment of Recurrent Pelvic Colorectal CancerUpdates in Surgery10.1007/978-88-470-5767-8_13 13. Pain Control and Palliative Treatments Marco Cascella1 , Francesca Bifulco, Barbara Di Caprio and Arturo Cuomo (1) Department of Anesthesia, Endoscopy, and Cardiology, Istituto Nazionale…
