Complementary and Alternative Therapies
Biologically based therapy Year Indication Subjects Comparator Duration Response on CAM (%) Response on comparator (%) Author, Ref I. Herbal therapies: Aloe vera 2004 UC 44 Placebo 4 weeks 30…
Treatment of Acute Severe Ulcerative Colitis
Fig. 37.1 Sigmoid colon: Diffuse inflammation with loss of vascular pattern and ulceration, typical of the pattern seen in ulcerative colitis He continued to do well, and maintenance infliximab therapy…
Medical Treatment of Perianal Crohn’s Disease Fistulae
Author, year N Drug, dose Rx time Response drug Response placebo p-value Willoughby et al., 1971 [75] 3 AZA, 2 mg/kg/day 24 weeks 0/2 (0%) 0/1 (0%) NR Rhodes et…
Nutritional Management of Inflammatory Bowel Disease
Circulating inflammatory cytokines Medications, particularly glucocorticoids Malnutrition Resting energy expenditure Height, weight, and pubertal status Gender Physical activity Body composition studies have often been limited by the large proportion of…
Antibiotic Therapy
© Springer International Publishing AG 2017Petar Mamula, Andrew B. Grossman, Robert N. Baldassano, Judith R. Kelsen and Jonathan E. Markowitz (eds.)Pediatric Inflammatory Bowel Disease10.1007/978-3-319-49215-5_26 26. Antibiotic Therapy Lindsey Albenberg1, 2 , Howard Kader3 and Adam Paul4 (1) Perelman School of Medicine, The…
Fecal Biomarkers in Inflammatory Bowel Disease
Fig. 19.1 Fecal calprotectin (Taken from Vogl et al. [5]) Tertiary and quaternary structures of S100A8 and S100A9 proteins presented by ribbon diagrams: (a) S100A8 homodimer; individual subunits are shown…
Laboratory Evaluation of Inflammatory Bowel Disease
Test Findings Significance Complete blood count and differential Anemia (microcytic, macrocytic, normocytic), thrombocytosis, leukocytosis Anemia: Assess severity of blood loss, evaluate for iron and other macronutrient deficiencies. Reported prevalence 16–77%…
Differential Diagnosis of Inflammatory Bowel Disease
Laboratory test Organism suggested or identified Microscopic stool examination Fecal leukocytes Invasive or cytotoxin-producing bacteria Trophozoïtes, cysts, oocysts, or spores Giardia lamblia, Entameoba histolytica, Schistosoma mansoni Spiral or S-shaped Gram-negative…
Puberty and Pediatric-Onset Inflammatory Bowel Disease
Hormone Stage/age Male Female Dehydroepiandrosterone Tanner I <89 <46 Sulfate (DHAS) (mcg/dl) Tanner II <81 15–113 Tanner III 22–126 42–162 Tanner IV 33–117 42–241 Tanner V 110–510 45–320 Luteinizing hormone…
Genetics of Inflammatory Bowel Diseases
Fig. 1.1 Associations of the IL12/IL23- and IL27-regulating genes with IBD in keeping with the TH1 and TH2/TH17 theory (Wang et al. [96]). Only the main proteins in these pathways…
