Management of Ileal, Appendiceal and Colorectal Neuroendocrine Tumors
Fig. 12.1 CT scan of patient with ileal NET and bulky lymph node metastases Fig. 12.2 Surgical specimen of a laparoscopic right colectomy (same case as Fig. 12.1) Twenty percent…
Pathological Analysis of Abdominal Neuroendocrine Tumors
Fig. 9.1 Features of neuroendocrine neoplasms as seen on fine-needle aspiration cytology. A well-differentiated tumor presents with regular cell morphology (a) and a low Ki-67 labeling index (b), while a…
Management of Gastric Neuroendocrine Tumors
Fig. 10.1 Gastric neuroendocrine carcinoma (NEC) Fig. 10.2 Gastroscopy showing a NEC of a gastric stump. The stomach was resected thirty years earlier for peptic ulcer Since type 4 G-NETs…
Hereditary Syndromes and Abdominal Neuroendocrine Tumors
Syndrome Cutaneous lesion Localization Frequency Age of onset MEN1 Multiple angiofibromas Facial Over 85% of MEN1 patients Before 40 years of age Multiple collagenomas Trunk, neck and upper limbs Over…
Neuroendocrine Tumors: a Nosologic Framework
Cell Type Hormones Produced Distribution alpha Glucagon Pancreas beta Insulin Pancreas delta Somatostatin Stomach, small intestine, pancreas, appendix, colon, rectum EC Serotonin Stomach, small intestine, pancreas, appendix, colon, rectum ECL…
Role of Functional Imaging in the Diagnosis of Neuroendocrine Tumors
Fig. 8.1 G2 pancreatic NET (Ki-67 12%) in a 48-year-old man. a Baseline negative FDG PET. b Baseline 68Ga-DOTA-peptide PET with evidence of pancreatic lesion. b1 Baseline 68Ga-DOTA-peptide PET with…
Management of Pancreatic and Duodenal Neuroendocrine Tumors
© Springer-Verlag Italia 2018Massimo Carlini (ed.)Abdominal Neuroendocrine TumorsUpdates in Surgeryhttps://doi.org/10.1007/978-88-470-3955-1_11 11. Management of Pancreatic and Duodenal Neuroendocrine Tumors Luca Landoni, Sara Cingarlini, Salvatore Paiella, Stefano Severi, Marco Miotto, Chiara Nessi, Elisabetta Grego, Maddalena Sansovini, Massimo Carlini and Claudio Bassi1 (1) General and Pancreatic Surgery…
Neuroendocrine Tumors Biomarkers
Fig. 5.1 Neoplastic causes of elevated Chromogranin A (CgA). CgA elevations occur in different types of NETs but are usually more pronounced in GEP-NETs (small intestinal, gastric, and pancreatic NETs)….
Sporadic Gastroenteropancreatic Neuroendocrine Tumors
Tumor Biologically active peptide Tumor sites (abdominal) Main symptoms/signs Carcinoid syndrome Serotonin, tachykinins Midgut, pancreas Diarrhea, abdominal pain, flushing Gastrinoma Gastrin Duodenum, pancreas Pain, diarrhea Insulinoma Insulin Pancreas Hypoglycemic symptoms…
Classification of Abdominal Neuroendocrine Tumors
Fig. 2.1 Histologic features of digestive neuroendocrine neoplasms as exemplified in the pancreas according to morphologic criteria for tumor grading. Well-differentiated neuroendocrine tumors of grade 1 exhibit organoid appearance featuring…
