Abdominal Key

  Type 1 Type 2 Type 3 Type 4 Frequency (%) 70–80 5–6 14–25 6–8 Age of occurrence 40–60 45 50 >60 Dimensions (mm) <10 <15 >20 >20 Features Multiple…

Well-differentiated tumor (G1-G2)1 Resectable extrahepatic disease 2 Type I or selected type II metastases 3 Future liver remnant ≥30% Low perioperative risk No carcinoid heart disease Primary NET resected or…

Fig. 12.1 CT scan of patient with ileal NET and bulky lymph node metastases Fig. 12.2 Surgical specimen of a laparoscopic right colectomy (same case as Fig. 12.1) Twenty percent…

Fig. 9.1 Features of neuroendocrine neoplasms as seen on fine-needle aspiration cytology. A well-differentiated tumor presents with regular cell morphology (a) and a low Ki-67 labeling index (b), while a…

Fig. 10.1 Gastric neuroendocrine carcinoma (NEC) Fig. 10.2 Gastroscopy showing a NEC of a gastric stump. The stomach was resected thirty years earlier for peptic ulcer Since type 4 G-NETs…

Syndrome Cutaneous lesion Localization Frequency Age of onset MEN1 Multiple angiofibromas Facial Over 85% of MEN1 patients Before 40 years of age Multiple collagenomas Trunk, neck and upper limbs Over…

Cell Type Hormones Produced Distribution alpha Glucagon Pancreas beta Insulin Pancreas delta Somatostatin Stomach, small intestine, pancreas, appendix, colon, rectum EC Serotonin Stomach, small intestine, pancreas, appendix, colon, rectum ECL…

Fig. 8.1 G2 pancreatic NET (Ki-67 12%) in a 48-year-old man. a Baseline negative FDG PET. b Baseline 68Ga-DOTA-peptide PET with evidence of pancreatic lesion. b1 Baseline 68Ga-DOTA-peptide PET with…

Fig. 5.1 Neoplastic causes of elevated Chromogranin A (CgA). CgA elevations occur in different types of NETs but are usually more pronounced in GEP-NETs (small intestinal, gastric, and pancreatic NETs)….