Cancer in the Kidney Transplant Recipient
Cancer type SIR Observed incidence/100,000 person-years Non-Hodgkin lymphoma 7.54 194 Lung 1.97 173 Liver 11.56 120 Kidney 4.65 97 Colorectum 1.24 80.9 Melanoma 2.38 49.2 Thyroid 2.95 30.7 Urinary bladder…
Biological Cancer Therapies and the Kidney
Class Examples Kidney toxicity Antiangiogenic therapy Bevacizumab, sunitinib, sorafenib, pazopanib, everolimus Hypertension, proteinuria, TMA, AKI EGFR inhibitors Cetuximab, erlotinib, gefitinib, lapatinib, panitumumab Hypomagnesemia, hypokalemia Multifunctional TKIs Imatinib, dasatinib, ponatinib, bosutinib…
Radiation Nephropathy
Fig. 12.1 Thrombotic microangiopathy. The figure showing changes of TMA (a hematoxylin and eosin stain, b periodic acid-Schiff stain) with peripheral capillary wall thickening and focal glomerular basement membrane duplication….
Chronic Kidney Disease (CKD) in Cancer Patients
Stage GFR (mL/min/1.73m2) Description 1 90+ Normal kidney function but urine or structural abnormalities 2 60–89 Mildly reduced kidney function 3a 45–59 Moderately reduced kidney function 3b 30–44 4 15–29…
Renal Cell Carcinoma and Chronic Kidney Disease
Fig. 10.1 Bidirectional interactions between CKD and RCC For those patients with mild CKD or no evidence of CKD prior to the diagnosis of RCC, the surgical procedure will have…
Acute Kidney Injury in Cancer Patients
Fig. 1.1 Causes and syndromes leading to acute kidney injury in cancer patients Prerenal Causes Sepsis and hypoperfusion are commonly reported causal etiologies of AKI in patients with cancer [22,…
Patient with Essential Hypertension and Left Ventricular Hypertrophy
(1) Department of Clinical and Molecular Medicine, University of Rome Sapienza St Andrea Hospital, Rome, Italy 1.1 Clinical Case Presentation A 54-year-old, Caucasian male, gardener, presented to the outpatient…
Patient with Essential Hypertension and Microalbuminuria
(1) Department of Clinical and Molecular Medicine, University of Rome Sapienza St Andrea Hospital, Rome, Italy 3.1 Clinical Case Presentation A 45-year-old, Caucasian female, postal employee, presented to the…
Patient with Essential Hypertension and Diastolic Dysfunction
(1) Department of Clinical and Molecular Medicine, University of Rome Sapienza St Andrea Hospital, Rome, Italy 2.1 Clinical Case Presentation A 44-year-old, Caucasian male, officer, presented to the Outpatient…
Patient with Essential Hypertension and High Pulse Pressure
(1) Department of Clinical and Molecular Medicine, University of Rome Sapienza St Andrea Hospital, Rome, Italy 6.1 Clinical Case Presentation An 81-year-old, Caucasian male, former CEO of chemical company,…
