Radical cystectomy is a standard treatment of nonmetastatic, muscle-invasive bladder cancer. Treatment with trimodality therapy consisting of maximal transurethral resection of the bladder tumor followed by concurrent chemotherapy and radiation…
Bladder cancer ranges from a low-grade variant to high-grade disease. Assessment for treatment depends on white light cystoscopy, however because of its limitations there is a need for improved visualization…
Samir S. Taneja, MD, Consulting Editor In the battlefield of Urologic Oncology, we face two distinct enemies. First, typically on the frontline, we are confronted with low-risk variants of urologic…
Arjun V. Balar, MD, Editor Matthew I. Milowsky MD, Editor Invasive urothelial cancer is a heterogeneous disease with a clear need to identify better methods to differentiate those patients who…
Testicular germ cell cancer is one of the most curable cancers. Most patients are treated during their reproductive years, making infertility a significant quality of life issue after successful treatment….
Key points • Potentially long-term life-threatening complications, including second malignant neoplasms, cardiovascular disease, neurotoxicity and ototoxicity, pulmonary complications, hypogonadism, and nephrotoxicity have accompanied the remarkable successes of testicular cancer treatment….
Retroperitoneal recurrences following retroperitoneal lymph node dissection (RPLND) are rare events and, with few exceptions, should be regarded as either surgical or technical failures, or a result of inappropriate modifications…
Surgery remains an integral component of treating metastatic testicular germ cell tumors outside the retroperitoneum. Defining the role of surgery in extraretroperitoneal (ERP) disease can be challenging because metastases can…
Germ cell tumors of the testis have an overall survival rate greater than 90% as a result of a successful multidisciplinary approach to management. Late relapse affects a subset of…
Key points • Patients with persistently elevated serum tumor markers should be monitored for marker kinetics and evaluated for nonviable cancer causes of marker elevation. • Desperation postchemotherapy retroperitoneal lymph…
