Management of Metastatic Bladder Tumours
Regimens Reference N OR (%) CR (%) Survival (months) P MVAC [6] 120 36 13 12.5 <0.0002 Cisplatin 126 11 3 8.2 MVAC [7] 55 65 35 12.6 <0.05 CISCA…
Surgical Management of Bladder Cancer
1. Muscle invasive (≥T2) bladder cancer 2. Select patients with recurrent high grade T1 or CIS 3. BCG and intravesical chemotherapy failures: high grade T1, with concomitant CIS, multifocal disease…
Invasive Bladder Cancer: Combined Modality Treatment
Parameter Limitation Examples Laboratory methodology New assay system Standardization in progress What is “normal”? Optimal technology? e.g. I-H vs. FISH? e.g. RNA vs. protein? Inter-laboratory variation Lab test applied to…
Principles of Chemotherapy for Genitourinary Cancer
Fig. 13.1 Cell cycle (Reprinted from Kalmadi and Raghavan [43]. With permission from Springer Verlag) 1. Cells remain quiescent in a resting phase (G0), which may be prolonged over years;…
Life After Urological Cancer – Psychological Issues
Fig. 16.1 Comparison of emotional distress by cancer site Hinz and colleagues [11] looked at the degree of psychological distress (anxiety and depression) in urological cancer patients over a period…
Intravesical Therapy for Bladder Cancer
57. Herr HW, Dalbagni G. Defining bacillus Calmette-Guerin refractory superficial bladder tumors. J Urol. 2003;169(5):1706–8.PubMed 58. Solsona E, Iborra I, Dumont R, et al. The 3-month clinical response to intravesical…
Chemotherapy for Testicular Cancer
Variable 0 1 2 3 Primary site Gonadal Retroperitoneal Mediastinal Response 1st line CR/PRm- PRm+/SD PD PFI >3 months ≤3 months AFP at salvage normal <1,000 >1,000 LBB at salvage…
The Role of Radiotherapy in Testicular Cancer
© Springer-Verlag London 2015Vinod H. Nargund, Derek Raghavan and Howard M. Sandler (eds.)Urological Oncology10.1007/978-0-85729-482-1_30 30. The Role of Radiotherapy in Testicular Cancer Sophie D. Fossa1 and Jan Oldenburg2 (1) Department of Oncology, Oslo University Hospital, Montebello, Oslo, Norway (2)…
Epidemiology, Biology, and Genetics of Adult Male Germ Cell Tumors
Characteristic Risk estimates or comment [reference] Disorders of male development Cryptorchidism Five to nine-fold increased risk, 10 % lifetime risk [11, 12] Disorders of sex development Variable, depends on specific…
Nephron-Saving Procedures: Ablative Techniques (Non-surgical) Radiofrequency Ablation (RFA), High-Intensity Focused Ultrasound (HIFU), Cryotherapy
Fig. 23.1 (a) Central 2.2 cm tumour abutting the collecting system. 6 F ureteric catheter has been inserted and noted next to the lesion. (b) The RF probe is inserted…
