Alcoholic Liver Disease
Alcoholic Liver Disease (Am J Gastro 1998;93:2022-36) DEFINITION: Clinical spectrum includes fatty liver (occurs in days & is reversible), alcoholic hepatitis and alcoholic cirrhosis; Only 20% of alcoholics develop the…
Alcoholic Liver Disease (Am J Gastro 1998;93:2022-36) DEFINITION: Clinical spectrum includes fatty liver (occurs in days & is reversible), alcoholic hepatitis and alcoholic cirrhosis; Only 20% of alcoholics develop the…
Acute Liver Failure (Fulminant Hepatic Failure) (Hepatology 2005;41:1179-97) DEFINITION: Acute hepatic disease + coagulopathy (INR >1.5) + encephalopathy (without a history of prior liver disease, except Wilson’s & AIH) Fulminant…
Abscess of Liver DEFINITION: Two types of liver abscess; Areas affected by either: Right lobe only (65%), Both lobes (30%), Left lobe only (5%) Pyogenic, usually arise from intraabdominal infections…
α1-Antitrypsin Deficiency DEFINITION: Deficiency in alpha-1-antitrypsin (α1-AT) characterized by liver and/or lung injury Other inheritable forms of liver disease: Hemochromatosis, Wilson’s EPIDEMIOLOGY: 1 in 2,000 is homozygous and 1 in…
Ulcerative Colitis (Am J Gastroenterol. 2004;99:1371-1385.; Gastroenterology. 2004;126:1582-1592.; N Engl J Med. 2002; 347:417-429) DEFINITION: Idiopathic inflammation of the colonic mucosa (as opposed to Crohn’s which is transmural and any…
Treatment: Crohn’s Disease & Ulcerative Colitis Goals of therapy for IBD: Induction and maintenance of remission (Gastroenterology. 2006;130:935-987) CATEGORY: 5ASA (5 AMINO SALICYLIC ACID) Induction/maintenance for UC; Induction/maintenance for very…
Microscopic & Radiation Colitis MICROSCOPIC COLITIS (Am J Gastroenterol 2004, 94:451-65) Definition: Idiopathic colitides with mild inflammatory changes diagnosed only by colorectal biopsy and thus only microscopically Microscopic colitis is…
Crohn’s Disease (Aliment Pharmacol Ther. 2003;18:263-77. Am J Gastroenterol. 2001;96:635-43. N Engl J Med 2002; 347:417-29) DEFINITION: Idiopathic or nonspecific transmural inflammation of the any segment of the GI tract…