Gastrointestinal Manifestations of Immunodeficiency
Since the last edition of this book, advances in the understanding of the adaptive and innate immune systems have led to the characterization of a number of novel primary immune…
Pediatric Polyposis Syndromes
Children and adolescents with gastrointestinal polyps may present symptoms including rectal bleeding, abdominal pain, or intussusception. Alternatively, they may be asymptomatic, having been referred, because either an adult family member…
Ulcerative Colitis in Children and Adolescents
Ulcerative colitis (UC) is an important pediatric gastrointestinal disease, given its potential for significant morbidity and even mortality during childhood, its chronicity, and its premalignant nature. Although significant advances in…
Intestinal and Multivisceral Transplantation: An Update in the Milieu of Gut Rehabilitation
Significant advances have been made in the management of patients with intestinal failure, including pediatric patients. These advances include medical gut rehabilitation, autologous reconstruction, bowel lengthening, and visceral transplantation. Gut…
Enteric Parasites
Enteric parasites are important agents of disease throughout the world. Although the frequency and severity of parasitic diseases are most extreme in the developing world, changes in worldwide travel, immigration,…
Chronic Intestinal Pseudo-Obstruction
Chronic intestinal pseudo-obstruction (CIPO) is defined as repetitive or continuous symptoms and signs of bowel obstruction in the absence of a fixed, lumen-occluding lesion. CIPO is a result of the…
Infectious Diarrhea
According to the Centers for Disease Control and Infection, diarrheal disease is the second leading cause of death in children younger than 5 years of age worldwide. It is also…
Short Bowel Syndrome
Definition Short bowel syndrome (SBS) refers to the sum of functional impairments that result from a critical reduction in intestinal length. In the absence of therapy, features of SBS include…
Celiac Disease
Definition Celiac disease (CD) is an immune-mediated systemic disorder elicited by the ingestion of wheat gliadin and related prolamins in genetically susceptible individuals, characterized by a variable combination of gluten-dependent…
Protracted Diarrhea
The intestine is a complex organ system with the unique ability to digest and absorb food while also coordinating complicated motility and hosting a distinctive immune system. When abnormalities occur…
