Introduction Gastroparesis, also called delayed gastric emptying, is a chronic digestive condition where the stomach fails to properly empty, causing sometimes debilitating symptoms, including nausea, vomiting, pain, and distention/bloating, which…
Introduction Normal gastric motor function requires coordinated interaction between the central nervous system (CNS), the enteric nervous system (ENS), interstitial cells of Cajal (ICC), and smooth muscle cells (SMCs). Gastroparesis…
Key points • Epidemiological studies show that the incidence of gastroparesis in women is four times higher than men. • Female sex hormones fluctuate during different hormonal stages including the…
Introduction In gastroparesis, there is abnormal function of extrinsic vagal innervation, smooth muscle, enteric nervous system, or pacemakers in the stomach wall, specifically, the interstitial cells of Cajal (ICCs) or…
Abbreviations EFTB endoscopicfull-thickness biopsy EMR endoscopic mucosal resection FTRD full-thickness resection device ICC interstitial cells of Cajal MP muscularis propria OTSC over-the-scope-clip Introduction Gastroparesis is a syndrome of delayed gastric…
Case study HM is a 34 year old woman sent for a third opinion in gastroenterology. Her symptoms include near daily nausea, epigastric fullness, early satiety and bloating. Symptoms started…
Introduction Gastroparesis is a symptomatic condition of delayed gastric emptying with no mechanical obstruction . There are several etiologies of gastroparesis, including diabetic gastroparesis and postsurgical gastroparesis. In many patients,…
Introduction The NIH Gastroparesis Clinical Research Consortium (GpCRC) was started in 2005 to improve the understanding of the pathogenesis and natural history of gastroparesis of all etiologies and to advance…
Introduction Gastroparesis (GP) is a disorder of delayed gastric emptying in the absence of mechanical obstruction that manifests with abdominal pain, nausea/vomiting, bloating and early satiety. Total or subtotal gastrectomy…
Key points (1) Gastric electrical stimulation (GES) is a therapy providing neurostimulation via two electrodes implanted in the gastric smooth muscle. (2) The predominant mechanism of action of GES is…
