Liver Disease in Systemic Conditions

Jul 4, 2016 by in NEPHROLOGY Comments Off on Liver Disease in Systemic Conditions

The specific type of amyloid cannot be determined by the hematoxylin and eosin (H&E) findings. However, amyloid deposits can be further subtyped on liver biopsy by immunostains, by laser microdissection…

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Pediatric Cholestatic Liver Disease

Jul 4, 2016 by in NEPHROLOGY Comments Off on Pediatric Cholestatic Liver Disease

Clinical Findings Most infants with biliary atresia are term infants with normal birth weights. Infants present within the first 1 to 6 weeks of life with jaundice, pale stools, and…

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Autoimmune Hepatitis

Jul 4, 2016 by in NEPHROLOGY Comments Off on Autoimmune Hepatitis

TREATMENT. Individuals with AIH are treated by immunosuppression. Steroids, with or without azathioprine, are commonly used, and remission can be achieved in up to 80% of cases. Individuals who do…

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Benign and Malignant Biliary Tumors

Jul 4, 2016 by in NEPHROLOGY Comments Off on Benign and Malignant Biliary Tumors

Bile duct hamartomas can be single or multiple. Most are small (less than 10 mm), but occasional cases can be very large, up to 20 cm, with large dilated biliary…

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Iron Overload Disease

Jul 4, 2016 by in NEPHROLOGY Comments Off on Iron Overload Disease

Iron Absorption Most iron is absorbed in the duodenum and proximal jejunum. Heme iron is disassociated from globin and then taken up by the enterocytes. Dietary non-heme iron requires additional…

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Pediatric Benign and Malignant Tumors

Jul 4, 2016 by in NEPHROLOGY Comments Off on Pediatric Benign and Malignant Tumors

Nonetheless, infantile hemangiomas do have a risk of developing malignancy and should be examined for areas of atypia. Architectural atypia can include papillary tufts (Fig. 18.2) as well as solid…

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Granulomatous Disease

Jul 4, 2016 by in NEPHROLOGY Comments Off on Granulomatous Disease

At a practical diagnostic pathology level, the etiology of granulomas in the liver will most often not be evident by histology alone. Nonetheless, there can be clues that will help…

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The Almost Normal Liver Biopsy

Jul 4, 2016 by in NEPHROLOGY Comments Off on The Almost Normal Liver Biopsy

The specific entities in Table 3.1 are discussed in detail in the relevant chapters of this book, but this table provides a useful compilation of subtle biopsy diagnoses to consider…

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Other Tumors of the Liver

Jul 4, 2016 by in NEPHROLOGY Comments Off on Other Tumors of the Liver

LYMPHOMA Most lymphomas involving the liver are not primary lymphomas. Essentially, any lymphoma can, at some point, involve the liver as it spreads from its site of origin (Fig. 22.3,…

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Other Infections of the Liver

Jul 4, 2016 by in NEPHROLOGY Comments Off on Other Infections of the Liver

TICK-BORNE DISEASES Ticks can transmit a variety of infections, including protozoa, bacteria, and viruses. Most of the infections are not primarily hepatic in their manifestations, but the bacterial infections in…

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