Triggers for Intervention

Feb 9, 2018 by in Uncategorized Comments Off on Triggers for Intervention

Fig. 9.1 A schematic representation of true biological progression of the disease that can occur if initially low-grade cancer cells or histologically normal cells transform into higher-grade cancer cells However,…

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Risk-Based Selection for Active Surveillance

Feb 9, 2018 by in Uncategorized Comments Off on Risk-Based Selection for Active Surveillance

Fig. 6.1 Definition of overdiagnosis (From Etzoioni [55]. Used with permission) Fig. 6.2 Association of different treatment strategies with life expectancy and risk of PCa progression. The downhill slope between…

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Tissue-Based Markers for Risk Prediction

Feb 9, 2018 by in Uncategorized Comments Off on Tissue-Based Markers for Risk Prediction

Company/test name Molecular type Primary endpoints Prolaris – cell cycle progression Gene expression (RNA quantification) Risk of biochemical recurrence, metastasis, and disease-specific mortality Genome DX – Decipher biopsy Gene expression (RNA quantification)…

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Research Questions in Active Surveillance

Feb 9, 2018 by in Uncategorized Comments Off on Research Questions in Active Surveillance

Name N Intervention Outcome Nordic lifestyle 2011 24 Vigorous exercise > = 3 ×/week, rye PCa progression Diet in PCa 2011 464 Dietary education and telephone counseling × 2 years Clinical progression, TTP…

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