Outline Introduction 3 Medaka as a Model Animal for Kidney Research 4 General Advantages of Using Medaka 4 Notable Differences Between Humans (Mammals) and Medaka 4 An Example of Medaka…
Outline Introduction 167 The Concept of Endothelial Progenitor Cells 167 Endothelial Progenitor Cells as an Indicator of Cardiovascular Disease 168 Early Outgrowth Cells: Myeloid Endothelial Progenitor Cells 168 Circulating CD34…
Outline Introduction 19 Methodology for Organogenesis 20 Antigen Presentation 20 MHC Expression 21 Immune Response 21 Vascularization 22 Renal Organogenesis 23 Isotransplantation/Allotransplantation of Renal Primordia 23 Preservation Prior to Transplantation…
Outline Introduction 69 Lipid Mediators: Chemical Autacoids in Inflammation and Resolution 72 Lipoxins 72 Proresolving Pathways, Essential Fatty Acids and Resolution Indices 74 Aspirin is Resolution Friendly 74 Statins and…
Outline Introduction 93 Tissue Expression of Erythropoietin and the Erythropoietin Receptor 93 Erythropoietin in the Vascular System 94 Erythropoietin and the Endothelium 94 Erythropoietin and Endothelial Progenitor Cells 95 Erythropoietin…
Outline Introduction 103 Basic Biology of Mast Cells 104 Origin, Tissue Distribution and Heterogeneity of Mast Cells 104 Mast Cell Mediators 105 Receptors Expressed by Mast Cells 107 Model Systems…
Outline Introduction 125 Injury, Repair and Regeneration of the Kidney 125 Macrophage Phenotype 126 Macrophages in Different Disease Models 127 Classically Activated Macrophages in Adriamycin Nephropathy 127 Wound-healing (IL-4/IL-13-stimulated, M2a)…
Outline Introduction 153 The Mesenchymal Stem Cell 153 Amniotic Fluid-derived Stem Cells 154 Bone Marrow Plasticity and Renal Repair 154 Mesenchymal Stem Cells Ameliorate Renal Injury and Accelerate Repair 156…
Outline Overview of T Cells in Kidney Diseases 141 Glomerulonephritis 143 Immune-mediated Glomerulonephritis 143 Non-immune-mediated Glomerulonephritis 143 Acute Kidney Injury 144 Ischemic Acute Kidney Injury 144 Sepsis-induced Acute Kidney Injury…
Introduction Despite advances in understanding the pathophysiology of acute kidney injury (AKI) and chronic kidney disease, treatment for kidney disease remains unsatisfactory. In this chapter, we briefly recount the importance…
