Inflammatory bowel disease (IBD) is an immune-mediated disease and involves a complex interplay of host genetics and environmental influences. Recent advances in the field, including data from genome-wide association studies…
The therapeutic approach in inflammatory bowel disease has evolved to target end-organ inflammation to heal intestinal mucosa and avoid structural damage. Objective therapeutic monitoring is required to achieve this goal….
Edward V. Loftus Jr, MD, Editor By the time this issue of Gastroenterology Clinics of North America is released, it will have been 16 years since infliximab was approved by…
Forthcoming Issues December 2014 Upper GI Bleeding Ian Gralnek, Editor March 2015 Gastroparesis Henry P. Parkman and Pankaj Jay Pasricha, Editors June 2015 Barrett’s Esophagus Prasad G. Iyer and Navtej…
Gary W. Falk, MD, MS, Consulting Editor The therapy of inflammatory bowel disease has changed dramatically in recent years with the advent of biologic therapy. Whereas therapy of inflammatory bowel…
Gastric antral vascular ectasia (GAVE) and portal hypertensive gastropathy (PHG) are important causes of chronic gastrointestinal bleeding. These gastric mucosal lesions are mostly diagnosed on upper endoscopy and can be…
Acute variceal bleeding is a potentially life-threatening complication of portal hypertension. Management consists of emergent hemostasis, therapy directed at hemodynamic resuscitation, protection of the airway, and prevention and treatment of…
Expert knowledge of endoscopic management of gastric varices is essential, as these occur in 20% of patients with portal hypertension. Bleeding is relatively uncommon, but carries significant mortality when this…
Acute variceal bleeding (AVB) is a milestone event for patients with portal hypertension. Esophageal varices bleed because of an increase in portal pressure that causes the variceal wall to rupture….
Acute variceal bleeding (AVB) is a potentially life-threatening complication of cirrhosis and portal hypertension. Combination therapy with vasoactive drugs and endoscopic variceal ligation is the first-line treatment in the management…
