Barrett’s Esophagus
Gary W. Falk, MD, MS, Consulting Editor The incidence of esophageal adenocarcinoma continues to increase at an alarming rate in the Western world. While the prognosis for early esophageal adenocarcinoma…
GASTROENTEROLOGY
Barrett’s Esophagus: New Insights and Progress
Prasad G. Iyer, MD, MSc, FACG, FASGE, AGAF, Editor Navtej S. Buttar, MD, Editor Barrett’s esophagus (BE) is currently a field in rapid evolution. A number of well established paradigms…
Current Status and Prospects for a Helicobacter pyloriVaccine
Helicobacter pylori infection contributes to a variety of gastric diseases. H pylori- associated gastric cancer is diagnosed in advanced stages, and a vaccine against H pylori is desirable in parts…
Screening to Identify and Eradicate Helicobacter pyloriInfection in Teenagers in Japan
The purpose of this study was to elucidate the prevalence and effect of Helicobacter pylori infection in Japanese teenagers. The study subjects were students ages 16 to 17 from one…
Rationale for a Helicobacter pyloriTest and Treatment Strategy in Gastroesophageal Reflux Disease
Conflicting data have been published on the effect of long-term proton pump inhibitor therapy on the gastric mucosa in Helicobacter pylori –infected subjects. In this article, the available data are…
Treatment Strategy for Gastric Mucosa-Associated Lymphoid Tissue Lymphoma
Recent trends and current knowledge on the diagnosis and treatment strategy for gastric mucosa-associated lymphoid tissue (MALT) lymphoma are reviewed. Helicobacter pylori infection plays the causative role in the pathogenesis,…
Helicobacter pyloriEradication to Eliminate Gastric Cancer
Helicobacter pylori eradication therapy for chronic gastritis achieved world-first coverage by the Japanese national health insurance scheme in 2013, making a dramatic decrease of gastric cancer–related deaths more realistic. Combining…
Molecular Pathogenesis of Helicobacter pylori -Related Gastric Cancer
Helicobacter pylori infection plays a crucial role in gastric carcinogenesis. H pylori exerts oncogenic effects on gastric mucosa through complex interaction between bacterial virulence factors and host inflammatory responses. On…
Gastric Cancer Risk in Patients with Helicobacter pyloriInfection and Following Its Eradication
As Helicobacter pylori is a first-class carcinogen, eradication of the infection would be expected to be a beneficial measure for the (primary) prevention of gastric cancer. Given the natural history…
When Is Endoscopic Follow-up Appropriate After Helicobacter pyloriEradication Therapy?
The effect of Helicobacter pylori eradication treatment needs confirmation in patients with persistent symptoms and in those with complicated peptic ulcer. Endoscopic surveillance after eradication is needed in patients with…
