Introduction In gastroparesis, there is abnormal function of extrinsic vagal innervation, smooth muscle, enteric nervous system, or pacemakers in the stomach wall, specifically, the interstitial cells of Cajal (ICCs) or…
Abbreviations EFTB endoscopicfull-thickness biopsy EMR endoscopic mucosal resection FTRD full-thickness resection device ICC interstitial cells of Cajal MP muscularis propria OTSC over-the-scope-clip Introduction Gastroparesis is a syndrome of delayed gastric…
Case study HM is a 34 year old woman sent for a third opinion in gastroenterology. Her symptoms include near daily nausea, epigastric fullness, early satiety and bloating. Symptoms started…
Introduction Gastroparesis is a symptomatic condition of delayed gastric emptying with no mechanical obstruction . There are several etiologies of gastroparesis, including diabetic gastroparesis and postsurgical gastroparesis. In many patients,…
Introduction The NIH Gastroparesis Clinical Research Consortium (GpCRC) was started in 2005 to improve the understanding of the pathogenesis and natural history of gastroparesis of all etiologies and to advance…
Introduction Gastroparesis (GP) is a disorder of delayed gastric emptying in the absence of mechanical obstruction that manifests with abdominal pain, nausea/vomiting, bloating and early satiety. Total or subtotal gastrectomy…
Key points (1) Gastric electrical stimulation (GES) is a therapy providing neurostimulation via two electrodes implanted in the gastric smooth muscle. (2) The predominant mechanism of action of GES is…
Introduction Gastroparesis can be a debilitating condition that affects patient quality of life. Over the past two decades, there has been a dramatic increase in hospital admissions and health care…
The term “gastroparesis” implies a partial or complete paralysis of the stomach as a result of muscle or nerve dysfunction. As this book will attest, gastroparesis is far more complex…
Gastroparesis is a heterogeneous syndrome with variable clinical manifestations. Some patients present with regurgitation-predominant symptoms suggestive of gastroesophageal reflux disease, but effortless regurgitation of undigested foods after meals and at…
